For many years, the methods of cancer treatment are usually surgery, chemotherapy and
radiation therapy. Although these methods help to improve the condition, most tumors still …

Adoptive cell therapy (ACT) harnesses the capabilities of immune cells to fight complex
diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …

Chimeric antigen receptor (CAR) T-cell therapy is an effective, individualized
immunotherapy, and novel treatment for hematologic malignancies. Six commercial CAR-T …

The release of cytokines by chimeric antigen receptor (CAR) T-cells and tumor resident
immune cells defines a significant part of CAR T-cell functional activity and patient immune …

Background Chimeric antigen receptor T (CAR-T) cell immunotherapy is becoming one of
the most promising treatments for hematological malignancies, however, complications such …

Chimeric antigen receptor T-cells, known as CAR-T cells, represent a promising
breakthrough in the realm of adoptive cell therapy. These T-cells are genetically engineered …

Background Patient susceptibility to cytokine release syndrome (CRS) resulting from
immune‐modulating chemotherapy has profound implications for clinical outcome. This is …

Despite improvements in therapy, multiple myeloma remains incurable. Chimeric antigen
receptor (CAR) T-cells have recently been demonstrated to be highly effective in the …

Chimeric antigen receptor T (CAR-T) cells technology has been successfully used in the
treatment of B cell-derived hematological tumors and multiple myeloma. CAR-T cells are …

Chimeric antigen receptor T cell therapy revolutionizes the field of cancer immunotherapy
and has been increasingly utilized in a variety of oncological settings with success …