Plant pathogenic microorganisms cause substantial yield losses in several economically
important crops, resulting in economic and social adversity. The spread of such plant …

RNAi is widely appreciated as a powerful regulator of mRNA translation in the cytoplasm of
mammalian cells. However, the presence and activity of RNAi factors in the mammalian …

Immunohistochemistry (IHC) combined with fluorescence microscopy provides an important
and widely used tool for researchers and pathologists to image multiple biomarkers in tissue …

Here we present a deep learning-based image analysis platform (DLAP), tailored to
autonomously quantify cell numbers, and fluorescence signals within cellular compartments …

Esophageal adenocarcinoma (EAC) develops from a chronic inflammatory environment
across four stages: intestinal metaplasia, known as Barrett's esophagus, low-and high-grade …

Exploring the tumour microenvironment provides insight into the unique interaction between
the host and tumour. Ultimately, its study improves understanding of how an individual …

Kinins are mediators of pain and inflammation and evidence suggests that the inducible
kinin B1 receptor (B1R) is involved in neuropathic pain (NP). This study investigates whether …

Normal fibroblasts produce extracellular matrix (ECM) components that form the structural
framework of tissues. Cancer-associated fibroblasts (CAFs) with an activated phenotype …

Microenvironment evaluation of intact tissue for analysis of cell infiltration and spatial
organization are essential in understanding the complexity of disease processes. The …

The tumor microenvironment (TME), composed of immune cells, antigens, and local soluble
factors, is integral to cancer development and progression. Traditional techniques such as …