Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

Phages differ substantially in the bacterial hosts that they infect. Their host range is
determined by the specific structures that they use to target bacterial cells. Tailed phages …

Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as
structural components of the virion. These enzymes appear as tail spike proteins (TSPs) …

The major constituent of the outer membrane of Gram-negative bacteria is
lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O …

Bacteria that cause life-threatening infections in humans are becoming increasingly difficult
to treat. In some instances, this is due to intrinsic and acquired antibiotic resistance …

Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …

Bacterial biofilms formed by pathogens are known to be hundreds of times more resistant to
antimicrobial agents than planktonic cells, making it extremely difficult to cure biofilm-based …

ABSTRACT A greater ethical conscience, new global rules and a modified perception of
ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo …

Bacteriophages (phages) are viruses that infect bacteria. The “predator–prey” interactions
are recognized as a potentially effective way to treat infections. Phages, as well as phage …

Highlights•Phages use structurally diverse receptor binding proteins (RBPs) to target
different cell wall structures.•RBPs play a critical role in spatial and temporal positioning of …