Antibacterial potential of chalcones and its derivatives against Staphylococcus aureus
L da Silva, IA Donato, CAC Gonçalves, JR Scherf… - 3 Biotech, 2023 - Springer
Chalcones are natural substances found in the metabolism of several botanical families.
Their structure consists of 1, 3-diphenyl-2-propen-1-one and they are characterized by …
Their structure consists of 1, 3-diphenyl-2-propen-1-one and they are characterized by …
Comprehensive Phytochemical Profiling, Biological Activities, and Molecular Docking Studies of Pleurospermum candollei: An Insight into Potential for Natural …
The purpose of this study was to find the biological propensities of the vegetable plant
Pleurospermum candollei by investigating its phytochemical profile and biological activities …
Pleurospermum candollei by investigating its phytochemical profile and biological activities …
Spectroscopic analysis by NMR, FT-Raman, ATR-FTIR, and UV-Vis, evaluation of antimicrobial activity, and in silico studies of chalcones derived from 2 …
J da Cunha Xavier, FWQ de Almeida-Neto… - Journal of Molecular …, 2021 - Elsevier
Six 2'-hydroxychalcones were synthesized and characterized by NMR, FT-Raman, ATR-
FTIR, and UV-Vis. These chalcones alone and in combination with the ciprofloxacin …
FTIR, and UV-Vis. These chalcones alone and in combination with the ciprofloxacin …
Synthesis, spectroscopic characterization and antibacterial evaluation by chalcones derived of acetophenone isolated from Croton anisodontus Müll. Arg.
PT Da Silva, J da Cunha Xavier, TS Freitas… - Journal of molecular …, 2021 - Elsevier
Chalcones and their derivatives have been widely studied at research institutions and
industries, in order to verify their biological properties against various diseases. In this work …
industries, in order to verify their biological properties against various diseases. In this work …
[HTML][HTML] Antibacterial and antibiotic modifying activity, ADMET study and molecular docking of synthetic chalcone (E)-1-(2-hydroxyphenyl)-3-(2, 4-dimethoxy-3 …
JE Rocha, TS de Freitas, J da Cunha Xavier… - Biomedicine & …, 2021 - Elsevier
A large number of infections are caused by multi-resistant bacteria worldwide, adding up to
a figure of around 700,000 deaths per year. Because of that many strategies are being …
a figure of around 700,000 deaths per year. Because of that many strategies are being …
Chalcones reverse the anxiety and convulsive behavior of adult zebrafish
MKA Ferreira, AW da Silva, AL dos Santos Moura… - Epilepsy & Behavior, 2021 - Elsevier
In the treatment of anxiety and seizures, drugs of the benzodiazepine (BZD) class are used,
which act on the Central Nervous System (CNS) through the neurotransmitter gamma …
which act on the Central Nervous System (CNS) through the neurotransmitter gamma …
Synthesis of chalcones and their antimicrobial and drug potentiating activities
ATL Dos Santos, JB de Araújo-Neto, MMC da Silva… - Microbial …, 2023 - Elsevier
The increased resistance of microorganisms to antimicrobial drugs makes it necessary to
search for new active compounds, such as chalcones. Their simple chemical structure …
search for new active compounds, such as chalcones. Their simple chemical structure …
In vitro and in silico studies of chalcones derived from natural acetophenone inhibitors of NorA and MepA multidrug efflux pumps in Staphylococcus aureus
TS Freitas, JC Xavier, RLS Pereira, JE Rocha… - Microbial …, 2021 - Elsevier
Bacterial resistance induced by efflux pumps is a frequent concern in clinical treatments
involving multi-resistant bacteria. Staphylococcus aureus is a microorganism responsible for …
involving multi-resistant bacteria. Staphylococcus aureus is a microorganism responsible for …
Structural characterization, DFT calculations, ADMET studies, antibiotic potentiating activity, evaluation of efflux pump inhibition and molecular docking of chalcone (E) …
J da Cunha Xavier… - Journal of Molecular …, 2021 - Elsevier
Chalcones are open-chain flavonoids characterized by two aromatic rings joined by a three-
carbon α, β-unsaturated carbonyl system. Over the last several years, chalcones have …
carbon α, β-unsaturated carbonyl system. Over the last several years, chalcones have …
Synthesis, crystal structure, ATR-FTIR, FT-Raman and UV spectra, structural and spectroscopic analysis of (3E)‐4‐[4‐(dimethylamine) phenyl] but‐3‐en‐2‐one
Chalcones are a large and promising source of molecules that can be used for drug
development, as they have a wide variety of pharmacological activities associated with their …
development, as they have a wide variety of pharmacological activities associated with their …