Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Epidemiology and risk factors of uterine fibroids

D Pavone, S Clemenza, F Sorbi, M Fambrini… - Best practice & research …, 2018 - Elsevier
Risk factors, both modifiable and non-modifiable, are associated with the development of
fibroids. These include age, race, endogenous and exogenous hormonal factors, obesity …

Uterine fibroids: burden and unmet medical need

A Al-Hendy, ER Myers, E Stewart - Seminars in reproductive …, 2017 - thieme-connect.com
Uterine fibroids affect a wide cross-section of the population, with prevalence, symptom
severity, and overall disease burden generally higher among black women, likely due to …

Uterine fibroids and infertility

D Freytag, V Günther, N Maass, I Alkatout - Diagnostics, 2021 - mdpi.com
Infertility is a disease of the reproductive system defined by the failure to achieve a clinical
pregnancy after 12 months or more of regular unprotected sexual intercourse. Uterine …

Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth

AE Commandeur, AK Styer… - Human Reproduction …, 2015 - academic.oup.com
BACKGROUND Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle
tumors of the uterus. In the USA, the lifetime risk for women developing uterine leiomyomas …

Uterine fibroids: pathogenesis and interactions with endometrium and endomyometrial junction

A Ciavattini, J Di Giuseppe, P Stortoni… - Obstetrics and …, 2013 - Wiley Online Library
Uterine leiomyomas (fibroids or myomas) are benign tumors of uterus and clinically
apparent in a large part of reproductive aged women. Clinically, they present with a variety …

Uterine fibroids: hiding in plain sight

EA Stewart, RA Nowak - Physiology, 2022 - journals.physiology.org
Uterine fibroids (leiomyomas) are present in> 75% of women and can cause serious
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …

Uterine fibroids and diet

A Tinelli, M Vinciguerra, A Malvasi, M Andjić… - International journal of …, 2021 - mdpi.com
Uterine myomas or fibroids are the most common benign female tumors of the reproductive
organs, associated with significant morbidity and quality of life impairment. Several …

Vitamin D status in women with uterine leiomyomas

A Paffoni, E Somigliana, P Vigano'… - The Journal of …, 2013 - academic.oup.com
Context: Recent in vitro and in vivo experimental evidence supports a role of vitamin D
insufficiency as an important factor in the development of uterine leiomyomas. However …

[HTML][HTML] Role of vitamin D in uterine fibroid biology

S Brakta, JS Diamond, A Al-Hendy, MP Diamond… - Fertility and sterility, 2015 - Elsevier
Objective To provide a detailed summary of current scientific knowledge on uterine fibroids
(leiomyomas) in vitro and in in vivo animal models, as well as to postulate the potential role …