DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

Molecular simulation has become an integral part of the DNA/RNA nanotechnology
research pipeline. In particular, understanding the dynamics of structures and single …

First evidence of geometrical patterns and defined distances of biomolecules as
fundamental parameters to regulate receptor binding and cell signaling have emerged …

Insulin binds the insulin receptor (IR) and regulates anabolic processes in target tissues.
Impaired IR signalling is associated with multiple diseases, including diabetes, cancer and …

DNA molecules that store genetic information in living creatures can be repurposed as
building blocks to construct artificial architectures, ranging from the nanoscale to the …

The clustering of death receptors (DRs) at the membrane leads to apoptosis. With the goal of
treating tumours, multivalent molecular tools that initiate this mechanism have been …

We present a net-shaped DNA nanostructure (called “DNA Net” herein) design strategy for
selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial …

Living cells possess a variety of transmembrane signaling systems that receive chemical
and physical cues from the environment and transduce this information into an intracellular …

Hybrid RNA: DNA origami, in which a long RNA scaffold strand folds into a target
nanostructure via thermal annealing with complementary DNA oligos, has only been …

Clustering of cell membrane receptors regulates cell behaviors. Although receptor clustering
plans have achieved wide applications in cancer therapy, it still remains challenging to …