Considering the retina as an extension of the brain provides a platform from which to study
diseases of the nervous system. Taking advantage of the clear optical media of the eye and …

Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal protein-
misfolding neurodegenerative diseases. TSEs have been described in several species …

Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a
group of neurodegenerative protein misfolding diseases that invariably cause death. TSEs …

The majority of bovine spongiform encephalopathy (BSE) cases have been ascribed to the
classical form of the disease. H-type and L-type BSE cases have atypical molecular profiles …

In 2006, a case of H-type bovine spongiform encephalopathy (BSE-H) was diagnosed in a
cow that was associated with a heritable polymorphism in the bovine prion protein gene …

Bovine spongiform encephalopathy (BSE) belongs to a group of fatal, transmissible protein
misfolding diseases known as transmissible spongiform encephalopathies (TSEs). All TSEs …

Abstract Sporadic Creutzfeldt-Jakob disease (sCJD) is the most commonly diagnosed
human prion disease caused by the abnormal misfolding of the 'cellular'prion protein (PrP C) …

Proteinopathies result from aberrant folding and accumulation of specific proteins. Currently,
there is a lack of knowledge about the factors that influence disease progression, making …

Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) that affects
sheep and goats. Sheep and goats can be infected with scrapie as lambs or kids via contact …

Objective—To determine the usefulness of retina samples for detection of disease-
associated prion protein by use of a commercially available enzyme immunoassay (EIA) …