4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

for digital applications (smartphones, etc.). These versions are abridged and thus, for more
detailed information, the user should always access to the full text version of the guidelines …

In this paper the Working Group on Myocardial and Pericardial Disease proposes a revised
definition of dilated cardiomyopathy (DCM) in an attempt to bridge the gap between our …

For many neuromuscular diseases (NMDs), cardiac disease represents a major cause of
morbidity and mortality. The management of cardiac disease in NMDs is made challenging …

Objectives: The aim of this study was to analyze the long-term follow-up of dilated
cardiolaminopathies. Background: Lamin A/C (LMNA) gene mutations cause a variety of …

Mutations in genes encoding proteins associated with the linker of nucleoskeleton and
cytoskeleton (LINC) complex within the nuclear envelope cause different diseases with …

The laminopathies are a diverse group of conditions caused by mutations in the LMNA gene
(MIM* 150330). LMNA encodes the nuclear envelope proteins lamin A and lamin C by …

Background Sudden cardiac death is frequent in patients with lamin A/C gene (LMNA)
mutations and may be related to ventricular arrhythmias (VA). Objective To evaluate a …

Mutations in LMNA, the gene encoding the nuclear membrane proteins, lamins A and C,
produce cardiac and muscle disease. In the heart, these autosomal dominant LMNA …

This international multidisciplinary document is intended to guide electrophysiologists,
cardiologists, other clinicians, and health care professionals in caring for patients with …