Discovering multifaceted role of vanillic acid beyond flavours: Nutraceutical and therapeutic potential
Background Vanillic acid is a phenolic compound, found in various dietary sources and
medicinal plants. Apart from its extraction from these biological sources, it is also …
medicinal plants. Apart from its extraction from these biological sources, it is also …
[HTML][HTML] Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review
Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …
[HTML][HTML] Plant constituents and thyroid: A revision of the main phytochemicals that interfere with thyroid function
G Di Dalmazi, C Giuliani - Food and Chemical Toxicology, 2021 - Elsevier
In the past few decades, there has been a lot of interest in plant constituents for their
antioxidant, anti-inflammatory, anti-microbial and anti-proliferative properties. However …
antioxidant, anti-inflammatory, anti-microbial and anti-proliferative properties. However …
[HTML][HTML] Identification and characterization of phytochemicals and constituents in Desmodium velutinum stem using high-performance liquid chromatography (HPLC)
The aim of this study was to analyse and identify phytochemicals and bioactive constituents
present in Desmodium velutinum stem. Fresh stems of Desmodium velutinum were air-dried …
present in Desmodium velutinum stem. Fresh stems of Desmodium velutinum were air-dried …
Coptisine, the Characteristic Constituent from Coptis chinensis, Exhibits Significant Therapeutic Potential in Treating Cancers, Metabolic and Inflammatory Diseases
Q Lu, Y Tang, S Luo, Q Gong, C Li - The American Journal of …, 2023 - World Scientific
Naturally derived alkaloids belong to a class of quite significant organic compounds.
Coptisine, a benzyl tetrahydroisoquinoline alkaloid, is one of the major bioactive …
Coptisine, a benzyl tetrahydroisoquinoline alkaloid, is one of the major bioactive …
Promising Role of Alkaloids in the Prevention and Treatment of Thyroid Cancer and Autoimmune Thyroid Disease: A Comprehensive Review of the Current Evidence
G Di Dalmazi, C Giuliani, I Bucci, M Mascitti… - International Journal of …, 2024 - mdpi.com
Thyroid cancer (TC) and thyroid autoimmune disorders (AITD) are among the most common
diseases in the general population, with higher incidence in women. Chronic inflammation …
diseases in the general population, with higher incidence in women. Chronic inflammation …
Structure‐based study to identify alkaloids as promising cytochrome P450 (CYP1A1) inhibitors: An in silico approach using virtual screening, molecular dynamic …
Carcinogens present in smokeless tobacco (SLT) like tobacco‐specific nitrosamines can be
metabolized by the cytochrome P450 (CYP450) enzyme. Functionally, the CYP450 enzyme …
metabolized by the cytochrome P450 (CYP450) enzyme. Functionally, the CYP450 enzyme …
The Effect of Natural Plant Products in the Management of Autoimmune Diseases Along with Photodynamic Therapy
Due to the high prevalence and inefficiency of the already existing treatment of autoimmune
diseases, researchers are investigating new treatment modalities for these diseases. One of …
diseases, researchers are investigating new treatment modalities for these diseases. One of …
Piperine increases striatal levels of DA and TH and decreases α-syn and Aβ42 deposition in PDD mice by regulting autophagy: downexpression Beclin-1 and LC3B …
L Huang, X Zhong, Z Zhou, Y Cai, M Deng - Applied Biological Chemistry, 2022 - Springer
Piperine, the major pharmacological ingredient of pepper, can delay the procession of
neuropharmacological effects, but its effects and mechanisms on Parkinson's disease …
neuropharmacological effects, but its effects and mechanisms on Parkinson's disease …
TULP3 NLS inhibition: an in silico study to hamper cargo transport to nucleus
TULP3 is involved in cell regulation pathways including transcription and signal
transduction. In some pathological states like in cancers, increased level of TULP3 has been …
transduction. In some pathological states like in cancers, increased level of TULP3 has been …