Antibiotics and other agents that perturb the synthesis or integrity of the bacterial cell
envelope trigger compensatory stress responses. Focusing on Bacillus subtilis as a model …

Daptomycin is a cyclic lipopeptide antibiotic, which was discovered in 1987 and entered the
market in 2003. To date, it serves as last resort antibiotic to treat complicated skin infections …

Daptomycin is a highly efficient last-resort antibiotic that targets the bacterial cell membrane.
Despite its clinical importance, the exact mechanism by which daptomycin kills bacteria is …

The microbial membrane serves as a biological barrier that separates the interior of cells
from the external environment, thus playing an important role in tolerance to stress …

Prokaryotes inhabiting in the deep sea vent ecosystem will thus experience harsh conditions
of temperature, pH, salinity or high hydrostatic pressure (HHP) stress. Among the fifty-two …

Bacteria remodel the fluidity of their membrane bilayer precisely via the incorporation of
proportionally more unsaturated fatty acids (or fatty acids with analogous properties) as …

Interaction between microbes affects the growth, metabolism and differentiation of members
of the microbial community. While direct and indirect competition, like antagonism and …

Microbes often face contrasted and fluctuating environmental conditions, to which they need
to adapt or die. Because membranes play a central role in regulating fluxes inward and …

Development of in vivo daptomycin resistance (DAP-R) among Staphylococcus aureus
clinical isolates, in association with clinical treatment failures, has become a major …

Antimicrobial peptides (AMPs) are a promising alternative to classical antibiotics in the fight
against multi-resistant bacteria. They are produced by organisms from all domains of life and …