Cancer cell plasticity during tumor progression, metastasis and response to therapy

A Pérez-González, K Bévant, C Blanpain - Nature cancer, 2023 - nature.com
Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …

The efficacy of PD-1/PD-L1 blockade in cold cancers and future perspectives

J Majidpoor, K Mortezaee - Clinical Immunology, 2021 - Elsevier
Colorectal cancer (CRC), and breast, ovarian, pancreatic and prostate cancers are generally
considered as low immune-reactive cancers that represent either limited infiltration of …

Angiogenesis as a hallmark of solid tumors-clinical perspectives

J Majidpoor, K Mortezaee - Cellular Oncology, 2021 - Springer
Background Angiogenesis is a key and early step in tumorigenesis, and is known as a
hallmark of solid tumors and a key promoter of tumor recurrence. Unlike normal tissue …

Anticancer activity of propolis and its compounds

E Forma, M Bryś - Nutrients, 2021 - mdpi.com
Propolis is a natural material that honey bees (Apis mellifera) produce from various
botanical sources. The therapeutic activity of propolis, including antibacterial, antifungal, and …

The current knowledge concerning solid cancer and therapy

M Najafi, J Majidpoor, H Toolee… - Journal of biochemical …, 2021 - Wiley Online Library
Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis

HS Tuli, J Kaur, K Vashishth, K Sak, U Sharma… - Archives of …, 2023 - Springer
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …

The impact of hypoxia on immune state in cancer

K Mortezaee, J Majidpoor - Life sciences, 2021 - Elsevier
Hypoxia is a known feature of solid tumors and a critical promoter of tumor hallmarks.
Hypoxia influences tumor immunity in a way favoring immune evasion and resistance …

[HTML][HTML] Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications

J Majidpoor, K Mortezaee - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Interleukin-6 (IL-6) is a multi-tasking cytokine that represents high activity in patients
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and cancer. High …

[HTML][HTML] Cancer-associated fibroblasts: Key criminals of tumor pre-metastatic niche

G Dong, P Chen, Y Xu, T Liu, R Yin - Cancer Letters, 2023 - Elsevier
Cancer-associated fibroblasts (CAFs) are abundant and important components of the
tumour mesenchyme, and have been extensively studied for their role in primary tumours …

[HTML][HTML] Breast cancer: molecular mechanisms of underlying resistance and therapeutic approaches

M Tufail, J Cui, C Wu - American journal of cancer research, 2022 - ncbi.nlm.nih.gov
Breast cancer (BC) affects over 250,000 women in the US each year. Drug-resistant cancer
cells are responsible for most breast cancer fatalities. Scientists are developing novel …