[HTML][HTML] Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

PC Calder, N Bosco, R Bourdet-Sicard, L Capuron… - Ageing research …, 2017 - Elsevier
Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

The role of immunosenescence in the development of age-related diseases

T Fülöp, G Dupuis, JM Witkowski… - Revista de investigacion …, 2016 - medigraphic.com
Aging is a complex phenomenon leading to numerous changes in the physiological systems
of the body. One of the most important changes, called immunosenescence, occurs in the …

Big data analytics in medical engineering and healthcare: methods, advances and challenges

L Wang, CA Alexander - Journal of medical engineering & …, 2020 - Taylor & Francis
Big data analytics are gaining popularity in medical engineering and healthcare use cases.
Stakeholders are finding big data analytics reduce medical costs and personalise medical …

Inflammaging and human longevity in the omics era

D Monti, R Ostan, V Borelli, G Castellani… - Mechanisms of Ageing …, 2017 - Elsevier
Inflammaging is a recent theory of aging originally proposed in 2000 where data and
conceptualizations regarding the aging of the immune system (immunosenescence) and the …

Multi-omics integration—a comparison of unsupervised clustering methodologies

G Tini, L Marchetti, C Priami… - Briefings in …, 2019 - academic.oup.com
With the recent developments in the field of multi-omics integration, the interest in factors
such as data preprocessing, choice of the integration method and the number of different …

[HTML][HTML] Inflammaging and brain: Curcumin and its beneficial potential as regulator of microglia activation

A Cianciulli, R Calvello, M Ruggiero, MA Panaro - Molecules, 2022 - mdpi.com
Inflammaging is a term used to describe the tight relationship between low-grade chronic
inflammation and aging that occurs during physiological aging in the absence of evident …

[HTML][HTML] Anti-aging effects of calorie restriction (CR) and CR mimetics based on the senoinflammation concept

DH Kim, EJ Bang, HJ Jung, SG Noh, BP Yu, YJ Choi… - Nutrients, 2020 - mdpi.com
Chronic inflammation, a pervasive feature of the aging process, is defined by a continuous,
multifarious, low-grade inflammatory response. It is a sustained and systemic phenomenon …

[HTML][HTML] The peculiar aging of human liver: a geroscience perspective within transplant context

C Morsiani, MG Bacalini, A Santoro, P Garagnani… - Ageing research …, 2019 - Elsevier
An appraisal of recent data highlighting aspects inspired by the new Geroscience
perspective are here discussed. The main findings are summarized as follows: i) liver has to …

[HTML][HTML] The human organism as an integrated interaction network: recent conceptual and methodological challenges

K Lehnertz, T Bröhl, T Rings - Frontiers in Physiology, 2020 - frontiersin.org
The field of Network Physiology aims to advance our understanding of how physiological
systems and sub-systems interact to generate a variety of behaviors and distinct …

[HTML][HTML] Resilience integrates concepts in aging research

D Promislow, RM Anderson, M Scheffer, B Crespi… - Iscience, 2022 - cell.com
Aging research is unparalleled in the breadth of disciplines it encompasses, from
evolutionary studies examining the forces that shape aging to molecular studies uncovering …