Mechanistic modelling of drug release from multi-layer capsules

B Kaoui, M Lauricella, G Pontrelli - Computers in biology and medicine, 2018 - Elsevier
We propose a novel in silico model for computing drug release from multi-layer capsules.
The diffusion problem in such heterogeneous layer-by-layer composite medium is described …

Numerical simulation of dissolution of solid particles in fluid flow using the SPH method

A Rahmat, M Barigou, A Alexiadis - … of Numerical Methods for Heat & …, 2020 - emerald.com
Purpose The purpose of this paper is to numerically study the dissolution of solid particles
using the smoothed particle hydrodynamics (SPH) method. Design/methodology/approach …

Numerical simulation of magnetic nanoparticle-based drug delivery in presence of atherosclerotic plaques and under the effects of magnetic field

M Varmazyar, MR Habibi, M Amini, AH Pordanjani… - Powder Technology, 2020 - Elsevier
The effect of stenosis on magnetonanoparticles (MNPs) distribution within the lumen is
presented in pulsatile blood flow in the presence of a non-uniform magnetic field. The effects …

Numerical investigation of ventilated cavitating flow in the wake of a circular cylinder

Z Wang, H Liu, Q Gao, Z Wang, Y Wang, G Wang… - Physical Review …, 2021 - APS
Ventilated cavitating flow of a circular cylinder is investigated by numerical simulation. The
coupled level set and volume of fluid method is used to capture the interface between the …

Solute release from an elastic capsule flowing through a microfluidic channel constriction

ZY Luo, BF Bai - Physics of Fluids, 2019 - pubs.aip.org
In recent years, microfluidic channels with narrow constrictions are extensively proposed as
a new but excellent possibility for advanced delivery technologies based on either natural or …

Computer simulations of drug release from a liposome into the bloodstream

B Kaoui - The European Physical Journal E, 2018 - Springer
I propose two-dimensional simulations of drug release from a liposome into the
bloodstream. I perform the fluid-structure coupling, between the particles deformation (the …

Dissolution characteristics of solutes with different shapes using the moving particle semi-implicit method

K Zhang, ZQ Zhou, PD Han, ZG Sun, G Xi - Physics of Fluids, 2022 - pubs.aip.org
Dissolution characteristics of solutes with different shapes are studied. To simulate the
process of dissolution, a diffusion and dissolution model based on the moving particle semi …

On the effects of surface corrugation on the hydrodynamic performance of cylindrical rigid structures

VK Krastev, G Amati, S Succi, G Falcucci - The European Physical Journal …, 2018 - Springer
In this work, we perform fully three-dimensional numerical simulations of the flow field
surrounding cylindrical structures characterized by different types of corrugated surface. The …

Coarse-grained simulations of diffusion controlled release of drugs from neutral nanogels: Effect of excluded volume interactions

JA Maroto-Centeno, M Quesada-Pérez - The Journal of Chemical …, 2020 - pubs.aip.org
The primary goal of this work is to assess the effect of excluded volume interactions on the
diffusion controlled release of drug molecules from a spherical, neutral, inert, and cross …

Algorithm to implement unsteady jump boundary conditions within the lattice Boltzmann method

B Kaoui - The European Physical Journal E, 2020 - Springer
An algorithm is proposed to implement unsteady jump boundary conditions in the lattice
Boltzmann method (LBM). This is useful for dealing with problems of mass transfer across …