Reverse vaccinology: developing vaccines in the era of genomics
A Sette, R Rappuoli - Immunity, 2010 - cell.com
The sequence of microbial genomes made all potential antigens of each pathogen available
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …
Microbial genomics and infectious diseases
DA Relman - New England Journal of Medicine, 2011 - Mass Medical Soc
Microbial Genomics and Infectious Diseases | New England Journal of Medicine Skip to main
content Access provided byTE WHATU ORA HEALTH NEW ZEALAND COUNTIES MANUKAU …
content Access provided byTE WHATU ORA HEALTH NEW ZEALAND COUNTIES MANUKAU …
ViPR: an open bioinformatics database and analysis resource for virology research
BE Pickett, EL Sadat, Y Zhang, JM Noronha… - Nucleic acids …, 2012 - academic.oup.com
Abstract The Virus Pathogen Database and Analysis Resource (ViPR, www. ViPRbrc. org) is
an integrated repository of data and analysis tools for multiple virus families, supported by …
an integrated repository of data and analysis tools for multiple virus families, supported by …
Reactome knowledgebase of human biological pathways and processes
L Matthews, G Gopinath, M Gillespie… - Nucleic acids …, 2009 - academic.oup.com
Abstract Reactome (http://www. reactome. org) is an expert-authored, peer-reviewed
knowledgebase of human reactions and pathways that functions as a data mining resource …
knowledgebase of human reactions and pathways that functions as a data mining resource …
Influenza research database: an integrated bioinformatics resource for influenza research and surveillance
RB Squires, J Noronha, V Hunt… - Influenza and other …, 2012 - Wiley Online Library
Please cite this paper as: Squires et al.(2012) Influenza research database: an integrated
bioinformatics resource for influenza research and surveillance. Influenza and Other …
bioinformatics resource for influenza research and surveillance. Influenza and Other …
PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells
KA Bussey, TL Bousse, EA Desmet, B Kim… - Journal of …, 2010 - Am Soc Microbiol
The direct infection of humans with highly pathogenic avian H5N1 influenza viruses has
suggested viral mutation as one mechanism for the emergence of novel human influenza A …
suggested viral mutation as one mechanism for the emergence of novel human influenza A …
TB database: an integrated platform for tuberculosis research
The effective control of tuberculosis (TB) has been thwarted by the need for prolonged,
complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the …
complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the …
Host-and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins
Highly pathogenic avian influenza A (HPAI) viruses of the H5N1 subtype have recently
emerged from avian zoonotic reservoirs to cause fatal human disease. Adaptation of HPAI …
emerged from avian zoonotic reservoirs to cause fatal human disease. Adaptation of HPAI …
PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology
JL McAuley, JE Chipuk, KL Boyd… - PLoS …, 2010 - journals.plos.org
With the recent emergence of a novel pandemic strain, there is presently intense interest in
understanding the molecular signatures of virulence of influenza viruses. PB1-F2 proteins …
understanding the molecular signatures of virulence of influenza viruses. PB1-F2 proteins …