Methanol is an ideal feedstock for biomanufacturing that can be beneficial for global carbon
neutrality; however, the toxicity of methanol limits the efficiency of methanol metabolism …

Lipids, commonly including phospholipids, sphingolipids, fatty acids, sterols, and
triacylglycerols (TAGs), are important biomolecules for the viability of all cells …

Phosphatidylserine (PS) is a negatively charged phospholipid that displays a highly uneven
distribution within cellular membranes, essential for establishment of cell polarity and other …

Testicular Leydig cells contain abundant cytoplasmic lipid droplets (LDs) as a cholesteryl-
ester store for releasing cholesterols as the precursor substrate for testosterone …

New antimycotic drugs are challenging to find, as potential target proteins may have close
human orthologs. We here focus on identifying metabolic targets that are critical for fungal …

Lipid droplets (LDs) are implicated in conditions of lipid and protein dysregulation. The fat
storage-inducing transmembrane (FIT; also known as FITM) family induces LD formation …

Phospholipases play a vital role in maintaining membrane phospholipids. In this study, we
found that deletion of the three major phospholipases B in Saccharomyces cerevisiae did …

Membrane lipid homeostasis is maintained by de novo synthesis, intracellular transport,
remodeling, and degradation of lipid molecules. Glycerophospholipids, the most abundant …

Genetic screens using high-throughput fluorescent microscopes have generated large
datasets, contributing many cell biological insights. Such approaches cannot tackle …

Alterations in lipid metabolism have been progressively documented as a characteristic
property of cancer cells. Though, human ABHD2 gene was found to be highly expressed in …