Entamoeba histolytica is the causative agent of human amoebiasis; it affects 50 million
people worldwide and causes approximately 100,000 deaths per year. Entamoeba …

Amebiasis is a disease caused by the unicellular parasite Entamoeba histolytica. In most
cases, the infection is asymptomatic but when symptomatic, the infection can cause …

Queuosine is a naturally occurring modified ribonucleoside found in the first position of the
anticodon of the transfer RNAs for Asp, Asn, His, and Tyr. Eukaryotes lack pathways to …

Amebiasis, a global intestinal parasitic disease, is due to Entamoeba histolytica. This
parasite, which feeds on bacteria in the large intestine of its human host, can trigger a strong …

Auranofin (AF), an antirheumatic agent, targets mammalian thioredoxin reductase (TrxR), an
important enzyme controlling redox homeostasis. AF is also highly effective against a …

During its life cycle, the unicellular parasite Entamoeba histolytica is challenged by a wide
variety of environmental stresses, such as fluctuation in glucose concentration, changes in …

Reactive sulfur species (RSS) like hydrogen sulfide (H2S) and cysteine persulfide (Cys-
SSH) emerged as key signaling molecules with diverse physiological roles in the body …

Actin is one of the most conserved, abundant, and ubiquitous proteins in all eukaryotes
characterised to date. Posttranslation modifications of actin modify the organisation of the …

Metronidazole (MNZ), the first line drug for amoebiasis and auranofin (AF), an emerging
antiprotozoan drug, are both inhibiting Entamoeba histolytica thioredoxin reductase. The …

This study aimed to know if alpha terthienyl (α-T) affects E. histolytica viability and to analyze
its effect on the actin cytoskeleton. Trophozoites of E. histolytica HM1-IMSS were treated with …