The pituitary adrenocorticotropic hormone (ACTH) plays a pivotal role in homeostasis and
stress response and is thus the major component of the hypothalamo–pituitary–adrenal axis …

Adipose tissue can be divided anatomically, histologically, and functionally into two major
entities white and brown adipose tissues (WAT and BAT, respectively). WAT is the primary …

The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone
ghrelin remain unclear. Based on qPCR analysis of FACS-purified gastric ghrelin cells …

Melanocortin hormone system plays a key role in maintaining the homeostasis of our body
via their neuro-immune-endocrine activities and regulates a diverse array of physiological …

With the ever-increasing burden of obesity and Type 2 diabetes, it is generally
acknowledged that there remains a need for developing new therapeutics. One potential …

G protein-coupled receptors (GPCRs) are a large family of cell surface receptors that are the
targets for many different classes of pharmacotherapy. The islets of Langerhans are central …

The melanocortin system is composed by the agonists adrenocorticotropic hormone and α, β
and γ-melanocyte-stimulating hormone, and two naturally occurring antagonists, agouti and …

Stress can compromise an animal's ability to conserve metabolic stores and participate in
energy-demanding activities that are critical for fitness. Understanding how wild animals …

The 5 known melanocortin receptors (MCs) have established physiological roles. With the
exception of MC2, these receptors can behave unpredictably, and since they are more …

It is becoming more common for poultry scientists to utilize direct and indirect measures of
stress hormones to monitor bird welfare. However, it has been clear that our understanding …