Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

Stimuli-responsive gene delivery nanocarriers for cancer therapy

Q Zhang, G Kuang, W Li, J Wang, H Ren, Y Zhao - Nano-Micro Letters, 2023 - Springer
Gene therapy provides a promising approach in treating cancers with high efficacy and
selectivity and few adverse effects. Currently, the development of functional vectors with …

Metal–organic framework nanoparticles

S Wang, CM McGuirk, A d'Aquino, JA Mason… - Advanced …, 2018 - Wiley Online Library
Due to their well‐defined 3D architectures, permanent porosity, and diverse chemical
functionalities, metal–organic framework nanoparticles (MOF NPs) are an emerging class of …

Nanoscale metal–organic frameworks for therapeutic, imaging, and sensing applications

K Lu, T Aung, N Guo, R Weichselbaum… - Advanced …, 2018 - Wiley Online Library
Nanotechnology has played an important role in drug delivery and biomedical imaging over
the past two decades. In particular, nanoscale metal–organic frameworks (nMOFs) are …

Metal–organic frameworks: a future toolbox for biomedicine?

RF Mendes, F Figueira, JP Leite, L Gales… - Chemical Society …, 2020 - pubs.rsc.org
The present review focuses on the use of Metal–Organic Frameworks,(MOFs) highlighting
the most recent developments in the biological field. This review assesses, in the first …

MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives

A Bieniek, AP Terzyk, M Wiśniewski, K Roszek… - Progress in Materials …, 2021 - Elsevier
We summarize recent advances in application of MOFs as therapeutic agents, drug carriers,
imaging agents and biosensors in cancer biomedicine. A holistic perspective is adopted to …

The next generation of platinum drugs: targeted Pt (II) agents, nanoparticle delivery, and Pt (IV) prodrugs

TC Johnstone, K Suntharalingam, SJ Lippard - Chemical reviews, 2016 - ACS Publications
The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,
but new platinum agents have been very slow to enter the clinic. Recently, however, there …

Nanomedicine applications of hybrid nanomaterials built from metal–ligand coordination bonds: nanoscale metal–organic frameworks and nanoscale coordination …

C He, D Liu, W Lin - Chemical reviews, 2015 - ACS Publications
The past two decades have witnessed rapid developments and innovations in
nanotechnology. 1− 10 Significant efforts have also been devoted to exploring clinical …

Nanoscale metal− organic frameworks for combined photodynamic & radiation therapy in cancer treatment

J Liu, Y Yang, W Zhu, X Yi, Z Dong, X Xu, M Chen… - Biomaterials, 2016 - Elsevier
Nanoscale metal organic frameworks (NMOFs) have shown great potential in biomedicine
owing to their structural/chemical diversities, high molecular loading capacities, and intrinsic …

Nanomedicine of synergistic drug combinations for cancer therapy–Strategies and perspectives

RX Zhang, HL Wong, HY Xue, JY Eoh… - Journal of Controlled …, 2016 - Elsevier
Nanomedicine of synergistic drug combinations has shown increasing significance in
cancer therapy due to its promise in providing superior therapeutic benefits to the current …