Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms

TC Marcink, G Zipursky, W Cheng, K Stearns… - Science …, 2023 - science.org
Paramyxoviruses—including important pathogens like parainfluenza, measles, and Nipah
viruses—use a receptor binding protein [hemagglutinin-neuraminidase (HN) for …

[HTML][HTML] Respiratory pathogenic microbial infections: a narrative review

Y Long, Y Zheng, C Li, Z Guo, P Li… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Respiratory infectious diseases have long been recognised as a substantial global
healthcare burden and are one of the leading causes of death worldwide, particularly in …

How a paramyxovirus fusion/entry complex adapts to escape a neutralizing antibody

TC Marcink, G Zipursky, EB Sobolik, K Golub… - Nature …, 2024 - nature.com
Paramyxoviruses including measles, Nipah, and parainfluenza viruses are public health
threats with pandemic potential. Human parainfluenza virus type 3 (HPIV3) is a leading …

Unraveling dynamics of paramyxovirus-receptor interactions using nanoparticles displaying hemagglutinin-neuraminidase

X Wu, M Goebbels, O Debski-Antoniak… - PLoS …, 2024 - journals.plos.org
Sialoglycan-binding enveloped viruses often possess receptor-destroying activity to avoid
being immobilized by non-functional decoy receptors. Sialic acid (Sia)-binding …

Human parainfluenza virus 3 field strains undergo extracellular fusion protein cleavage to activate entry

K Stearns, G Lampe, R Hanan, T Marcink, S Niewiesk… - Mbio, 2024 - journals.asm.org
ABSTRACT Human parainfluenza virus 3 (HPIV3) infection is driven by the coordinated
action of viral surface glycoproteins hemagglutinin-neuraminidase (HN) and fusion protein …

[HTML][HTML] Changes of parainfluenza virus infection in children before and after the COVID-19 pandemic in Henan, China

L Li, R Jia, Y Zhang, H Sun, J Ma - The Journal of Infection, 2023 - ncbi.nlm.nih.gov
Infections of Streptococcus pneumoniae and Haemophilus influenza in children were
affected by the COVID-19 pandemic, which were reported by Li et al. 1 and Zhou et al. 2 in …

[PDF][PDF] In-silico Design of Multi-epitope Vaccine for Tackling Type-1 Parainfluenza Virus. Research & Reviews: A Journal of Bioinformatics. 2023; 10 (2): 30–46p

SS Zaid Khan, MM Rekha - Bioinformatics, 2023 - research-reels.com
Human parainfluenza viruses (HPIV) often cause breathing infections, particularly in kids
and infants. HPIV-1 is known for causing severe croup, yet no approved vaccines exist for …

[PDF][PDF] ヒトレスピロウイルス1 型の膜融合蛋白遺伝子ならびに膜融合蛋白の分子進化に関する研究

高橋知子 - paz.repo.nii.ac.jp
はインフルエンザウイルスなどに比し, 低いことが推定された. 一方, 選択圧解析からは, HRV1・F
蛋白には, その部位の機能, 構造ならびに感染性を維持するための負の選択圧が作用していること …

[引用][C] In-silico multi-epitope vaccine candidate against type-1 parainfluenza virus

Z Khan, H BV, S Patil - 2023 - europepmc.org
In-silico multi-epitope vaccine candidate against type-1 parainfluenza virus - Abstract - Europe
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