Association between Q192R PON1 genetic polymorphism and major adverse cardiovascular events in patients treated with clopidogrel: an updated meta-analysis
Background Clopidogrel's responsiveness may be affected by the paraoxonase-1 (PON1)
enzyme encoded by the Q192R PON1 genetic variant. We aimed to determine the …
enzyme encoded by the Q192R PON1 genetic variant. We aimed to determine the …
Cost-effectiveness of CYP2C19-guided antiplatelet therapy for acute coronary syndromes in Singapore
We evaluated the cost-effectiveness of a genotype-guided strategy among patients with
acute coronary syndromes using a decision-tree model based on the Singapore healthcare …
acute coronary syndromes using a decision-tree model based on the Singapore healthcare …
CYP2C19 loss-of-function alleles predicts clinical outcomes in East Asian patients with acute myocardial infarction undergoing percutaneous coronary intervention …
YW Chen, YJ Liao, WC Chang, TH Hsiao… - Frontiers in …, 2022 - frontiersin.org
Background CYP2C19 loss-of-function (LOF) alleles reduce the effectiveness of clopidogrel
and are associated with high rates of clinical events in patients undergoing percutaneous …
and are associated with high rates of clinical events in patients undergoing percutaneous …
Differences in the Proportion of CYP2C19 Loss-of-Function Between Cerebral Infarction and Coronary Artery Disease Patients
Y Shi, Y Yang, M Feng, W Ling, T Wei… - … Journal of General …, 2023 - Taylor & Francis
Background Cytochrome P450 2C19 (CYP2C19) genotypes and metabolic phenotypes
(extensive metabolizer (EM), intermediate metabolizer (IM), and poor metabolizer (PM)) are …
(extensive metabolizer (EM), intermediate metabolizer (IM), and poor metabolizer (PM)) are …
[HTML][HTML] Validating the Prognostic Utility of the ABCD-GENE Score in Asian Patients with Acute Coronary Syndrome Patients on Clopidogrel
CK Tan, DBC Wu, SYJ Tan, SS Imran… - European Cardiology …, 2023 - ncbi.nlm.nih.gov
Background The ABCD-GENE score, which links cytochrome P450 2C19 (CYP2C19)
phenotype and high platelet reactivity (HPR) to the risk of major adverse cardiovascular …
phenotype and high platelet reactivity (HPR) to the risk of major adverse cardiovascular …
脑卒中患者氯吡格雷抵抗与CYP2C19 基因多态性和P2Y12 受体的相关性研究.
杜安妮， 林牧， 蔡锐 - Journal of Modern Medicine & Health, 2023 - search.ebscohost.com
目的研究脑卒中患者氯吡格雷抵抗与CYP2C19 基因多态性和P2Y12 受体之间相关性.
方法选取2019 年1 月至2020 年12 月于贵州航天医院住院, 临床诊断为缺血性脑卒中患者298 …
方法选取2019 年1 月至2020 年12 月于贵州航天医院住院, 临床诊断为缺血性脑卒中患者298 …
CYP2C19 基因多态性与急性心肌梗死患者炎症指标, 临床预后的相关性
吴天源， 罗义， 吕磊， 谭文亮， 孙少喜 - 广州医药, 2022 - gzyyzz.cn
目的探讨急性心肌梗死患者细胞色素P450 酶基因(cytochrome P450, family 2, subfamily C,
polypeptide 19, CYP2C19) 多态性与高敏C-反应蛋白(hypersensitive C-reactive protein, hs …
polypeptide 19, CYP2C19) 多态性与高敏C-反应蛋白(hypersensitive C-reactive protein, hs …
动脉球囊损伤大鼠Akt, GSK-3β 表达及药物干预治疗.
葛华， 潘龙庆， 王天如， 王月… - Practical Pharmacy & …, 2021 - search.ebscohost.com
动脉球囊损伤大鼠Akt,GSK-3β 表达及药物干预治疗 Page 1 收稿日期:2021 -03 -15 作者单位:沈阳
医学院附属中心医院ꎬ辽宁沈阳110024 基金项目:辽宁省自然科学基金(2019-ZD-0338) DOI:10 …
医学院附属中心医院ꎬ辽宁沈阳110024 基金项目:辽宁省自然科学基金(2019-ZD-0338) DOI:10 …
Measuring preferences for CYP2C19 genotyping in patients with acute coronary syndrome – a discrete choice experiment
JWT Wee, WY Png, XY Wong, YH Kwan, YY Lin… - Future …, 2020 - Taylor & Francis
Aim: To evaluate the relative importance of CYP2C19 genotype-guided treatment attributes
to patients. Patients & methods: A discrete choice experiment questionnaire was …
to patients. Patients & methods: A discrete choice experiment questionnaire was …
Perspective on CYP2C19 genotyping test among patients with acute coronary syndrome – a qualitative study
WY Png, XY Wong, YH Kwan, YY Lin… - Future Cardiology, 2020 - Taylor & Francis
Aim: Identify factors patients consider regarding CYP2C19 genotyping test to guide choice of
antiplatelet therapy. Patients & methods: Patient's perception and attitude toward use of …
antiplatelet therapy. Patients & methods: Patient's perception and attitude toward use of …