Cancer cell plasticity during tumor progression, metastasis and response to therapy
A Pérez-González, K Bévant, C Blanpain - Nature cancer, 2023 - nature.com
Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …
Wound healing, fibroblast heterogeneity, and fibrosis
Fibroblasts are highly dynamic cells that play a central role in tissue repair and fibrosis.
However, the mechanisms by which they contribute to both physiologic and pathologic …
However, the mechanisms by which they contribute to both physiologic and pathologic …
[HTML][HTML] Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are diverse mesenchymal cells that participate in tissue homeostasis and
disease by producing complex extracellular matrix and creating signaling niches through …
disease by producing complex extracellular matrix and creating signaling niches through …
Cancers make their own luck: theories of cancer origins
A Jassim, EP Rahrmann, BD Simons… - Nature reviews …, 2023 - nature.com
Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …
Wound healing: cellular mechanisms and pathological outcomes
HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …
Nanomaterials and nanomaterials-based drug delivery to promote cutaneous wound healing
T Liu, Y Lu, R Zhan, W Qian, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Various factors could damage the structure and integrity of skin to cause wounds.
Nonhealing or chronic wounds seriously affect the well-being of patients and bring heavy …
Nonhealing or chronic wounds seriously affect the well-being of patients and bring heavy …
Umbilical cord-derived mesenchymal stem cell-derived exosomes combined pluronic F127 hydrogel promote chronic diabetic wound healing and complete skin …
J Yang, Z Chen, D Pan, H Li, J Shen - International journal of …, 2020 - Taylor & Francis
Purpose Chronic refractory wounds are a multifactorial comorbidity of diabetes mellitus with
the characteristic of impaired vascular networks. Currently, there is a lack of effective …
the characteristic of impaired vascular networks. Currently, there is a lack of effective …
The great escape: tumour cell plasticity in resistance to targeted therapy
S Boumahdi, FJ de Sauvage - Nature reviews Drug discovery, 2020 - nature.com
The success of targeted therapies in cancer treatment has been impeded by various
mechanisms of resistance. Besides the acquisition of resistance-conferring genetic …
mechanisms of resistance. Besides the acquisition of resistance-conferring genetic …
Wound healing: a cellular perspective
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
Opportunities and challenges of translational 3D bioprinting
SV Murphy, P De Coppi, A Atala - Nature biomedical engineering, 2020 - nature.com
Abstract 3D-printed orthopaedic devices and surgical tools, printed maxillofacial implants
and other printed acellular devices have been used in patients. By contrast, bioprinted living …
and other printed acellular devices have been used in patients. By contrast, bioprinted living …