Lung disease as a determinant of cognitive decline and dementia

JW Dodd - Alzheimer's research & therapy, 2015 - Springer
Almost 40 million people currently live with dementia but this is estimated to double over the
next 20 years; despite this, research identifying modifiable risk factors is scarce. There is …

[HTML][HTML] Strength of association between comorbidities and asthma: a meta-analysis

P Rogliani, R Laitano, J Ora, R Beasley… - European Respiratory …, 2023 - Eur Respiratory Soc
Background The strength of association between comorbidities and asthma has never been
ranked in relation to the prevalence of the comorbidity in the nonasthma population. We …

[HTML][HTML] Microglial priming through the lung–brain axis: The role of air pollution–induced circulating factors

CL Mumaw, S Levesque, C McGraw… - The FASEB …, 2016 - ncbi.nlm.nih.gov
Air pollution is implicated in neurodegenerative disease risk and progression and in
microglial activation, but the mechanisms are unknown. In this study, microglia remained …

Myrtenol ameliorates recognition memories' impairment and anxiety-like behaviors induced by asthma by mitigating hippocampal inflammation and oxidative stress in …

MA Bejeshk, AH Aminizadeh, E Jafari… - …, 2023 - karger.com
Introduction: Asthma is related to neurochemical alterations which affect brain functions and
lead to anxiety and cognitive dysfunctions. Myrtenol has sparked considerable interest due …

Neuroimaging and biomarker evidence of neurodegeneration in asthma

MA Rosenkranz, DC Dean III, BB Bendlin… - Journal of Allergy and …, 2022 - Elsevier
Background Epidemiologic studies have shown that Alzheimer's disease (AD) and related
dementias (ADRD) are seen more frequently with asthma, especially with greater asthma …

Comorbidity and dementia: a nationwide survey in Taiwan

TB Chen, SY Yiao, Y Sun, HJ Lee, SC Yang, MJ Chiu… - PLoS …, 2017 - journals.plos.org
Background Comorbid medical diseases are highly prevalent in the geriatric population,
imposing hardship on healthcare services for demented individuals. Dementia also …

Myrtenol inhalation mitigates asthma-induced cognitive impairments: an electrophysiological, behavioral, histological, and molecular study

K Esmaeilpour, E Jafari, F Rostamabadi… - Molecular …, 2024 - Springer
Asthma is an inflammatory disorder with significant health problems. It generally affects the
lungs but can also impact brain performance via several mechanisms. Some investigations …

Asthma, the central nervous system, and neurocognition: Current findings, potential mechanisms, and treatment implications

JL Kroll, T Ritz - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Accumulating behavioral evidence suggests that asthma is associated with cognitive
deficits. A number of studies have identified potential biological contributions to cognition in …

Asthma amplifies dementia risk: Evidence from CSF biomarkers and cognitive decline

AK Nair, CA Van Hulle, BB Bendlin… - … Research & Clinical …, 2022 - Wiley Online Library
Introduction Evidence from epidemiology, neuroimaging, and animal models indicates that
asthma adversely affects the brain, but the nature and extent of neuropathophysiological …

Respiratory disease and lower pulmonary function as risk factors for dementia: a systematic review with meta-analysis

TC Russ, M Kivimäki, GD Batty - Chest, 2020 - Elsevier
Background In addition to affecting the oxygen supply to the brain, pulmonary function is a
marker of multiple insults throughout life (including smoking, illness, and socioeconomic …