Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence

DJ Becker, GF Albery, MK Kessler… - Journal of Animal …, 2020 - Wiley Online Library
The prevalence and intensity of parasites in wild hosts varies across space and is a key
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …

The life aquatic: advances in marine vertebrate genomics

JL Kelley, AP Brown, NO Therkildsen… - Nature Reviews …, 2016 - nature.com
The ocean is hypothesized to be where life on earth originated, and subsequent
evolutionary transitions between marine and terrestrial environments have been key events …

Whole genomes reveal multiple candidate genes and pathways involved in the immune response of dolphins to a highly infectious virus

KC Batley, J Sandoval‐Castillo, CM Kemper… - Molecular …, 2021 - Wiley Online Library
Wildlife species are challenged by various infectious diseases that act as important
demographic drivers of populations and have become a great conservation concern …

Genome‐wide association study of an unusual dolphin mortality event reveals candidate genes for susceptibility and resistance to cetacean morbillivirus

KC Batley, J Sandoval‐Castillo… - Evolutionary …, 2019 - Wiley Online Library
Infectious diseases are significant demographic and evolutionary drivers of populations, but
studies about the genetic basis of disease resistance and susceptibility are scarce in wildlife …

Contaminant exposure linked to cellular and endocrine biomarkers in Southern California bottlenose dolphins

ML Trego, E Hoh, A Whitehead, NM Kellar… - … science & technology, 2019 - ACS Publications
Cetaceans in the Southern California Bight (SCB) are exposed to high levels of halogenated
organic contaminants (HOCs), which have previously been linked to impaired reproductive …

The marine mammal class II major histocompatibility complex organization

ALA Sá, B Breaux, TCT Burlamaqui, TC Deiss… - Frontiers in …, 2019 - frontiersin.org
Sirenians share with cetaceans and pinnipeds several convergent traits selected for the
aquatic lifestyle. Living in water poses new challenges not only for locomotion and feeding …

Immune effects of the neurotoxins ciguatoxins and brevetoxins

O Pierre, L Misery, M Talagas, R Le Garrec - Toxicon, 2018 - Elsevier
Abstract Ciguatoxins (CTXs) and brevetoxins (PbTxs) are phycotoxins that can accumulate
along the marine food chain and thus cause seafood poisoning in humans, namely …

Genomewide investigation of adaptation to harmful algal blooms in common bottlenose dolphins (Tursiops truncatus)

KM Cammen, TF Schultz, PE Rosel, RS Wells… - Molecular …, 2015 - Wiley Online Library
Harmful algal blooms (HAB s), which can be lethal in marine species and cause illness in
humans, are increasing worldwide. In the Gulf of Mexico, HAB s of Karenia brevis produce …

Sequence diversity and differences at the highly duplicated MHC-I gene reflect viral susceptibility in sympatric pinniped species

AK Gigliotti, WD Bowen, MO Hammill… - Journal of …, 2022 - academic.oup.com
Differences in disease susceptibility among species can result from rapid host–pathogen
coevolution and differences in host species ecology that affect the strength and direction of …

Evolution and organization of MHC II genes in Harbour porpoises: insights from long-read cetacean genome assemblies, whole genome re-sequencing and locus …

E Celemín, N Gusev, M Domínguez, K Havenstein… - Evolution, 2024 - authorea.com
Abstract The Major Histocompatibility Complex (MHC) is a central element in the vertebrate
immune system. While MHC genes are a common target of conservation genomic studies, it …