Bartonellae are considered to be emerging opportunistic pathogens. The bacteria are
transmitted by blood-sucking arthropods, and their hosts are a wide range of mammals …

The α‐proteobacterial genus Bartonella comprises a large number of facultative intracellular
pathogens that share a common lifestyle hallmarked by hemotrophic infection and arthropod …

Abstract Galectin-3-binding protein (Gal-3BP) is a ubiquitous and multifunctional secreted
glycoprotein originally identified and mainly studied in the context of neoplastic …

Gene transfer agents (GTAs) randomly transfer short fragments of a bacterial genome. A
novel putative GTA was recently discovered in the mouse-infecting bacterium Bartonella …

In biofilms, the bacterial community optimizes the strategies to sense the environment and to
communicate from cell to cell. A key player in the development of a bacterial biofilm is the …

Bacterial pathogens employ type IV secretion systems (T4SSs) for various purposes to aid in
survival and proliferation in eukaryotic hosts. One large T4SS subfamily, the conjugation …

Highlights•Bartonella effector proteins are essential for the primary stages of infection,
including dissemination from the dermal site of inoculation to the blood stream.•Bartonella …

Fic proteins are a family of proteins characterized by the presence of a conserved FIC
domain that is involved in the modification of protein substrates by the addition of phosphate …

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death among
non-contagious diseases in the world. PDE inhibitors are among current medicines …

The targeted pathogen-selective approach to drug development holds promise to minimize
collateral damage to the beneficial microbiome. The AB5-topology pertussis toxin (PtxS1 …