Primary hypothyroidism and quality of life
L Hegedüs, AC Bianco, J Jonklaas… - Nature Reviews …, 2022 - nature.com
In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic l
form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of …
form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of …
[HTML][HTML] Evidence-based use of levothyroxine/liothyronine combinations in treating hypothyroidism: a consensus document
Background: Fourteen clinical trials have not shown a consistent benefit of combination
therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these …
therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these …
[HTML][HTML] 2020 European Thyroid Association clinical practice guideline for the use of image-guided ablation in benign thyroid nodules
E Papini, H Monpeyssen, A Frasoldati… - European thyroid …, 2020 - etj.bioscientifica.com
Standard therapeutic approaches for benign thyroid lesions that warrant intervention are
surgery for cold and either surgery or radioiodine for autonomously functioning thyroid …
surgery for cold and either surgery or radioiodine for autonomously functioning thyroid …
Association of thyroid hormone therapy with quality of life and thyroid-related symptoms in patients with subclinical hypothyroidism: a systematic review and meta …
Importance The benefit of thyroid hormone therapy for subclinical hypothyroidism is
uncertain. New evidence from recent large randomized clinical trials warrants an update of …
uncertain. New evidence from recent large randomized clinical trials warrants an update of …
Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement
Background: A number of recent advances in our understanding of thyroid physiology may
shed light on why some patients feel unwell while taking levothyroxine monotherapy. The …
shed light on why some patients feel unwell while taking levothyroxine monotherapy. The …
Subclinical hypothyroidism
RP Peeters - New England Journal of Medicine, 2017 - Mass Medical Soc
Key Clinical Points Subclinical Hypothyroidism Subclinical hypothyroidism is defined as an
elevated thyrotropin level with a normal free thyroxine (T4) level. To confirm the diagnosis, a …
elevated thyrotropin level with a normal free thyroxine (T4) level. To confirm the diagnosis, a …
Thyroid hormone therapy for older adults with subclinical hypothyroidism
Background The use of levothyroxine to treat subclinical hypothyroidism is controversial. We
aimed to determine whether levothyroxine provided clinical benefits in older persons with …
aimed to determine whether levothyroxine provided clinical benefits in older persons with …
Nonsurgical, image-guided, minimally invasive therapy for thyroid nodules
H Gharib, L Hegedüs, CM Pacella… - The Journal of …, 2013 - academic.oup.com
Context: Nodular thyroid disease is very common. Most nodules are asymptomatic, are
benign by fine-needle aspiration, remain stable, and can be followed by observation alone …
benign by fine-needle aspiration, remain stable, and can be followed by observation alone …
Graves' disease
TF Davies, S Andersen, R Latif, Y Nagayama… - Nature reviews Disease …, 2020 - nature.com
Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is
the most common cause of hyperthyroidism and occurs at all ages but especially in women …
the most common cause of hyperthyroidism and occurs at all ages but especially in women …
[HTML][HTML] Disease-specific as well as generic quality of life is widely impacted in autoimmune hypothyroidism and improves during the first six months of levothyroxine …
Background Hypothyroidism is often diagnosed, and subsequently treated, due to health-
related quality of life (HRQL) issues. However, HRQL following treatment has never …
related quality of life (HRQL) issues. However, HRQL following treatment has never …