Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …

The LysR family of transcriptional regulators represents the most abundant type of
transcriptional regulator in the prokaryotic kingdom. Members of this family have a …

The Gram-negative bacterial envelope is an essential interface between the intracellular
and harsh extracellular environment. Envelope stress responses (ESRs) are crucial to the …

Yersinia enterocolitica is a heterogeneous group of strains, which are classified into 6
biogroups, and into more than 57 O serogroups. However, the human pathogenic strains …

Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including
the yop effector and the ysc type III secretion genes, is controlled by the transcriptional …

The initial binding of bacteria to host cells is crucial to the delivery of virulence factors and
thus is a key determinant of the pathogen's success. We report a multivalent adhesion …

Interest in arthropod-borne pathogens focuses primarily on how they cause disease in
humans. How they produce a transmissible infection in their arthropod host is just as critical …

The human pathogens Yersinia pseudotuberculosis and Yersinia enterocolitica cause
enterocolitis, while Yersinia pestis is responsible for pneumonic, bubonic, and septicaemic …

Enteric pathogens often cycle between virulent and saprophytic lifestyles. To endure these
frequent changes in nutrient availability and composition bacteria possess an arsenal of …

Yersinia pestis, the agent of plague, is transmitted to mammals by infected fleas. Y. pestis
exhibits a distinct life stage in the flea, where it grows in the form of a cohesive biofilm that …