Genome-guided approaches and evaluation of the strategies to influence bioprocessing assisted morphological engineering of Streptomyces cell factories

M Thakur, P Kumar, D Rajput, V Yadav, N Dhaka… - Bioresource …, 2023 - Elsevier
Streptomyces genera serve as adaptable cell factories for secondary metabolites with
various and distinctive chemical structures that are relevant to the pharmaceutical industry …

The protein interactome of the citrus Huanglongbing pathogen Candidatus Liberibacter asiaticus

EW Carter, OG Peraza, N Wang - Nature Communications, 2023 - nature.com
Abstract The bacterium Candidatus Liberibacter asiaticus (CLas) causes citrus
Huanglongbing disease. Our understanding of the pathogenicity and biology of this …

Cellular and molecular level host-pathogen interactions in Francisella tularensis: A microbial gene network study

SK Miryala, S Ramaiah - Computational Biology and Chemistry, 2022 - Elsevier
Due to the high infectivity and fatal effect on human population, Francisella tularensis (F.
tularensis) is classified as a potential biological warfare agent. The interaction between host …

Genomic and Transcriptomic Analysis of Bovine Pasteurella multocida Serogroup A Strain Reveals Insights Into Virulence Attenuation

L Zhan, J Zhang, B Zhao, X Li, X Zhang… - Frontiers in Veterinary …, 2021 - frontiersin.org
Pasteurella multocida is one of the primary pathogens of bovine respiratory disease (BRD),
and causes huge losses in the cattle industry. The Pm3 strain was a natural isolate, which is …

Protective efficacy and immune responses of largemouth bass (Micropterus salmoides) immunized with an inactivated vaccine against the viral hemorrhagic …

H Huang, X Lu, J Guo, Y Chen, M Yi, K Jia - Fish & Shellfish Immunology, 2024 - Elsevier
Viral hemorrhagic septicemia virus (VHSV) poses a significant threat to the aquaculture
industry, prompting the need for effective preventive measures. Here, we developed an …

Transcriptome of human neuroblastoma SH-SY5Y cells in response to 2B protein of enterovirus-A71

K Suanpan, P Srimanote, P Tongtawe… - Scientific Reports, 2022 - nature.com
Infection with enterovirus-A71 (EV-A71) can cause hand-foot-mouth disease associated with
fatal neurological complications. The host response to EV-A71 has not yet been fully …

Computational prediction of crucial genes involved in gonorrhea infection and neoplastic cell transformation: A multiomics approach

BS Ravindranath, G Ananya, CH Kumar… - Microbial …, 2024 - Elsevier
Neisseria gonorrheae, the causative agent of genitourinary infections, has been associated
with asymptomatic or recurrent infections and has the potential to form biofilms and induce …

Genome-scale protein interaction network construction and topology analysis of functional hypothetical proteins in Helicobacter pylori divulges novel therapeutic …

P Gollapalli, H Manjunatha, P Shetty - Microbial Pathogenesis, 2021 - Elsevier
The emergence and spread of multi-drug resistance among Helicobacter pylori (H. pylori)
strain raise more stakes for genetic research for discovering new drugs. The quantity of …

Subtractive genome mining in Xanthomonas citri pv. citri strain 306 for identifying novel drug target proteins coupled with in-depth protein-protein interaction and …

T Mahato, J Mandal, E Chatterjee… - Biochemical and …, 2025 - Elsevier
Citrus canker poses a serious threat to a highly significant citrus fruit crop, this disease
caused by one of the most destructive bacterial plant pathogens Xanthomonas citri pv. citri …

Functional insights of antibiotic resistance mechanism in Helicobacter pylori: Driven by gene interaction network and centrality-based nodes essentiality analysis

P Gollapalli, GT Selvan, HS Santoshkumar… - Microbial …, 2022 - Elsevier
Increased antibiotic resistance in Helicobacter pylori (H. pylori), a major human pathogen,
constitutes a substantial threat to human health. Understanding the pathophysiology and …