[PDF][PDF] Systematic review: co-crystal as efforts to improve physicochemical and bioavailability properties of oral solid dosage form
I Sopyan, B Alvin, KS Insan Sunan… - Int. J. Appl …, 2021 - researchgate.net
Water solubility and low bioavailability of active pharmaceutical ingredients are some of the
main challenges in the process of developing new drugs, especially drugs in oral solid …
main challenges in the process of developing new drugs, especially drugs in oral solid …
Crystal engineering as a scientific basis for modification of physicochemical properties of bioflavonoids
IA Selivanova, RP Terekhov - Russian Chemical Bulletin, 2019 - Springer
Flavonoids are of interest for pharmacy and medicinal chemistry due to a wide range of
biological activities. The major goal for the design of new drugs based on flavonoids is to …
biological activities. The major goal for the design of new drugs based on flavonoids is to …
A review on co-crystals of Herbal Bioactives for solubility enhancement: preparation methods and characterization techniques
Co-crystallization is a promising approach for improving physical and pharmacological
properties of API, viz., solubility, dissolution rate, stability, hygroscopicity, tablet ability …
properties of API, viz., solubility, dissolution rate, stability, hygroscopicity, tablet ability …
Flavonoids with glutathione antioxidant synergy: Influence of free radicals inflow
This report explores the antioxidant interaction of combinations of flavonoid–glutathione with
different ratios. Two different 2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid radical …
different ratios. Two different 2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid radical …
Improving dissolution rate of piperine by multicomponent crystal formation with saccharin
Piperine, a secondary metabolite of Piper nigrum L., has been known for its pharmacological
activities. However, the use of piperine is still limited due to the low solubility in water. The …
activities. However, the use of piperine is still limited due to the low solubility in water. The …
Uncovering Cocrystal Formation and Competition Mechanism of Polyhydroxy Natural Products: Cases of Quercetin, Hesperidin, Resveratrol, and Curcumin
D Li, W Chen, L Zhou, L Xu, F He, JYY Heng… - Crystal Growth & …, 2024 - ACS Publications
Understanding drug cocrystal formation and its competitive mechanism is important for
improving the physicochemical properties of drugs. In this article, the cocrystal formation of …
improving the physicochemical properties of drugs. In this article, the cocrystal formation of …
Compression force effect on characteristics of loratadine-succinic acid cocrystal prepared by slurry method
D Setyawan, A Paramanandana… - Journal of Research …, 2020 - repository.unair.ac.id
Loratadine belongs to second generation antihistamine (H1) drug and is known to form
cocrystal with succinic acid in stoichiometry of 1: 1 using slurry method. This study was …
cocrystal with succinic acid in stoichiometry of 1: 1 using slurry method. This study was …
Solid dispersion of quercetin-PVP K-30 and its effects on the antioxidant activity
Background: Quercetin (3, 3', 4', 5, 7-pentahydroxil-flavon) is a flavone and secondary
metabolite known as flavonoid. Quercetin belongs to class II BCS that has low solubility and …
metabolite known as flavonoid. Quercetin belongs to class II BCS that has low solubility and …
Cocrystal formation of loratadine-succinic acid and its improved solubility
D Setyawan, FR Adyaksa, HL Sari… - Journal of Basic and …, 2021 - degruyter.com
Objectives Loratadine belongs to Class II compound of biopharmaceutics classification
system (BCS) due its low solubility and high membrane permeability. Cocrystal is a system …
system (BCS) due its low solubility and high membrane permeability. Cocrystal is a system …
Crystal Engineering Approach in Physicochemical Properties Modifications of Phytochemical
DS Lutfiyah, L Fitriani, M Taher… - Science and …, 2022 - sciencetechindonesia.com
Phytochemicals have been used to reduce the risk of diseases and maintain good health
and well-being. However, most phytochemicals have a limitation in their physicochemical …
and well-being. However, most phytochemicals have a limitation in their physicochemical …