Antibiotic resistance: turning evolutionary principles into clinical reality

DI Andersson, NQ Balaban, F Baquero… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

Group B streptococcal colonization, molecular characteristics, and epidemiology

S Shabayek, B Spellerberg - Frontiers in microbiology, 2018 - frontiersin.org
Streptococcus agalactiae or group B streptococcus (GBS) is a leading cause of serious
neonatal infections. GBS is an opportunistic commensal constituting a part of the intestinal …

Biological and epidemiological features of antibiotic-resistant Streptococcus pneumoniae in pre-and post-conjugate vaccine eras: a United States perspective

L Kim, L McGee, S Tomczyk, B Beall - Clinical microbiology …, 2016 - Am Soc Microbiol
Streptococcus pneumoniae inflicts a huge disease burden as the leading cause of
community-acquired pneumonia and meningitis. Soon after mainstream antibiotic usage …

The role of integrative and conjugative elements in antibiotic resistance evolution

J Botelho, H Schulenburg - Trends in microbiology, 2021 - cell.com
Mobile genetic elements (MGEs), such as plasmids and integrative and conjugative
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …

A review of antibiotic resistance in Group B Streptococcus: the story so far

K Hayes, F O'Halloran, L Cotter - Critical reviews in microbiology, 2020 - Taylor & Francis
Abstract Group B Streptococcus (GBS) is the leading cause of neonatal disease worldwide,
and invasive disease in adults is becoming more prevalent. Currently, some countries adopt …

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131

NL Ben Zakour, AS Alsheikh-Hussain, MM Ashcroft… - MBio, 2016 - Am Soc Microbiol
Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli
clone worldwide and a major cause of urinary tract and bloodstream infections. Although …

Antimicrobial Resistance in Streptococcus spp

M Haenni, A Lupo, JY Madec - Microbiology spectrum, 2018 - Am Soc Microbiol
ABSTRACT The genus Streptococcus includes Gram-positive organisms shaped in cocci
and organized in chains. They are commensals, pathogens, and opportunistic pathogens for …

Incidence of invasive group B streptococcal disease and pathogen genotype distribution in newborn babies in the Netherlands over 25 years: a nationwide …

V Bekker, MW Bijlsma, D van de Beek… - The Lancet Infectious …, 2014 - thelancet.com
Background Group B streptococcus is the most common cause of neonatal infections. We
studied the clinical and molecular epidemiology of invasive group B streptococcus infection …

Group B streptococcal disease worldwide for pregnant women, stillbirths, and children: why, what, and how to undertake estimates?

JE Lawn, F Bianchi-Jassir, NJ Russell… - Clinical infectious …, 2017 - academic.oup.com
Improving maternal, newborn, and child health is central to Sustainable Development Goal
targets for 2030, requiring acceleration especially to prevent 5.6 million deaths around the …

The evolutionary puzzle of Escherichia coli ST131

JDD Pitout, TJ Finn - Infection, Genetics and Evolution, 2020 - Elsevier
The abrupt expansion of Escherichia coli sequence type (ST) 131 is unmatched among
Gram negative bacteria. In many ways, ST131 can be considered a real-world model for the …