Nutrition in thalassemia: a systematic review of deficiency, relations to morbidity, and supplementation recommendations

EK Goldberg, A Lal, EB Fung - Journal of pediatric hematology …, 2022 - journals.lww.com
Background: Reports of nutritional deficiencies in patients with thalassemia (Thal) are
common. Despite its importance, however, nutritionally focused research in Thal has been …

Total and ionized calcium and magnesium are significantly lowered in drug-naïve depressed patients: effects of antidepressants and associations with immune …

AH Al-Dujaili, HK Al-Hakeim, AJ Twayej… - Metabolic brain disease, 2019 - Springer
Major depressive disorder (MDD) is associated with alterations in calcium (Ca) and
magnesium (Mg), as well as circulating pro-and anti-inflammatory cytokines. Anti …

In Transfusion-Dependent Thalassemia Children, Increased Iron Overload is Associated with Lower Serum Alpha-Klotho, Which is Strongly Associated with Lower …

S Rouf Moustafa, H Kadhem Al-Hakeim… - Current Molecular …, 2023 - ingentaconnect.com
Background: Patients with transfusion-dependent thalassemia (TDT) show disorders in
calcium metabolism. The α-Klotho protein is predominantly expressed in tissues that are …

Associating pathways with diseases using single-cell expression profiles and making inferences about potential drugs

M Sharma, IP Jha, S Chawla, N Pandey… - Briefings in …, 2022 - academic.oup.com
Finding direct dependencies between genetic pathways and diseases has been the target of
multiple studies as it has many applications. However, due to cellular heterogeneity and …

Construction of an exposure-pathway-phenotype in children with depression due to transfusion-dependent thalassemia: Results of (un) supervised machine learning.

HK Al-Hakeim, AH Najm, SR Moustafa… - Journal of Affective …, 2021 - Elsevier
Background: Transfusion dependent thalassemia (TDT) patients are treated with continued
blood transfusions and show a higher prevalence of depression. TDT with consequent iron …

Evaluation of erythroferrone, hepcidin, and iron overload status in Iraqi transfusion-dependent β-thalassemia major patients

HNK Smesam, HAQ Albuthabhak, S Arjmand… - …, 2020 - Taylor & Francis
Patients with β-thalassemia major (β-TM) show ineffective erythropoiesis and iron overload,
which is the leading cause of mortality and organ injury. The present study aimed to …

Cytokine dependent hematopoietic cell linker (CLNK) is highly elevated in blood transfusion dependent beta-thalassemia major patients

HK Al-Hakeim, HH Al-Mayali, SR Moustafa… - Transfusion Clinique et …, 2021 - Elsevier
Background Transfusion-dependent β-thalassemia (TDT) is a severe form of thalassemia
caused by mutations in the β-globin gene, resulting in partial or complete deficiency of β …

In Transfusion-dependent Thalassemia, Increased Iron Overload is Associated with Lower Serum Alpha-klotho, Which is Strongly Associated with Lower Total and …

M Maes, SR Moustafa, HK Al-Hakeim, ZH Alhillawi - 2020 - preprints.org
Patients with transfusion-dependent thalassemia (TDT) show disorders in calcium
metabolism. The α-klotho protein is predominantly expressed in tissues that are involved in …

The Relationship of Calcyphosina with Lipid Profile in Polycystic Ovary Syndrome Women

S Ahmed, KF Al-Rawi, RM Murshid - Journal of Pharmaceutical …, 2022 - pnrjournal.com
Objectives: The current study was designed to monitor the relationship between Lipid Profile
and calcyphosin a level by studying thecorrelation of calcyphosin a concentration in blood …

Osmotic fragility in essential hypertension revisited: A correlation with Iron status and lipid profile

ZH Alhillawi, SRM Al-Ani… - Journal of Physics …, 2021 - iopscience.iop.org
Essential hypertension is a major public health associated with increased pressure on the
vascular walls and red blood cells (RBCs). In the present work, osmotic fragility (OSF) of …