p21Waf1/Cip1/Sdi1 was originally identified as an inhibitor of cyclin-dependent kinases, a
mediator of p53 in growth suppression and a marker of cellular senescence. p21 is required …

The germinal center (GC) is a unique histological structure found in peripheral lymphoid
organs. GCs provide an important source of humoral immunity by generating high affinity …

Background As a natural compound extracted from a variety of hot peppers, capsaicin has
drawn increasing attention to its anti-cancer effects against multiple human cancers …

RNA interference holds tremendous potential as a therapeutic approach of malignant
tumors. However, safe and efficient nanovectors are extremely lack for systemic delivery of …

The p53 tumor suppressor is embedded in a large gene network controlling diverse cellular
and organismal phenotypes. Multiple signaling pathways converge onto p53 activation …

The factor that binds to the inducer of short transcripts‐1 (FBI-1) is a transcription suppressor
and an important proto‐oncogene that plays multiple roles in carcinogenesis and …

ZBTB7A is a member of the POK family of transcription factors that possesses a POZ-domain
at the N-terminus and Krüppel-like zinc-finger at the c-terminus. ZBTB7A was initially …

Background Non-small cell lung cancer (NSCLC) remains one of the most important death-
related diseases, with poor effective diagnosis and less therapeutic biomarkers. LncRNA …

Purpose: Stargardt disease (STGD) is the most common form of inherited juvenile macular
degeneration. It is inherited as autosomal recessive trait (STGD1), although STGD3 and …

Transcription factors (TFs) consisting of zinc fingers combined with BTB (for broad-complex,
tram-track, and bric-a-brac) domain (ZBTB) are a highly conserved protein family that …