Type 2 diabetes is caused by chronic insulin resistance and progressive decline in beta-cell
function. Optimal beta-cell function and mass is essential for glucose homeostasis and beta …

Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

Type 2 diabetes mellitus (T2DM) is a complex, chronic and progressive metabolic disease,
which is characterized by relative insulin deficiency, insulin resistance, and high glucose …

The hormone islet amyloid polypeptide (IAPP, or amylin) plays a role in glucose
homeostasis but aggregates to form islet amyloid in type‐2 diabetes. Islet amyloid formation …

Abstract Type 2 diabetes (T2DM) is characterized by insulin resistance, defective insulin
secretion, loss of β-cell mass with increased β-cell apoptosis and islet amyloid. The islet …

Calcitonin was discovered over 50 yr ago as a new hormone that rapidly lowers circulating
calcium levels. This effect is caused by the inhibition of calcium efflux from bone, as …

Islet amyloid polypeptide (IAPP, amylin) is the major protein component of the islet amyloid
deposits associated with type 2 diabetes. The polypeptide lacks a well-defined structure in …

Human islet amyloid polypeptide (IAPP or amylin) is a 37‐residue hormone found as fibrillar
deposits in pancreatic extracts of nearly all type II diabetics. Although the cellular toxicity of …

The aggregation of specific proteins is hypothesized to cause several pathological
conditions, which are collectively known as amyloid disorders. The aggregation of peptides …

Substantial epidemiological evidence shows an increased risk for developing Alzheimer's
disease (AD) in people with diabetes. Yet the underlying molecular mechanisms still remain …