Topical losartan: practical guidance for clinical trials in the prevention and treatment of corneal scarring fibrosis and other eye diseases and disorders
SE Wilson - Journal of Ocular Pharmacology and Therapeutics, 2023 - liebertpub.com
Losartan is an angiotensin II receptor blocker (ARB) that impedes transforming growth factor
(TGF) beta signaling by inhibiting activation of signal transduction molecule extracellular …
(TGF) beta signaling by inhibiting activation of signal transduction molecule extracellular …
Main complications of photorefractive keratectomy and their management
L Spadea, F Giovannetti - Clinical Ophthalmology, 2019 - Taylor & Francis
Photorefractive keratectomy (PRK) was the first surface ablation procedure introduced for
the treatment of refractive errors and has been proven to be effective and safe. In some …
the treatment of refractive errors and has been proven to be effective and safe. In some …
Topical losartan for treating corneal fibrosis (haze): first clinical experience
AL Pereira-Souza, R Ambrósio Jr… - Journal of Refractive …, 2022 - journals.healio.com
PURPOSE: To report the first clinical experience with topical losartan for treating a case of
severe corneal haze after complicated laser in situ keratomileusis (LASIK). METHODS: A 36 …
severe corneal haze after complicated laser in situ keratomileusis (LASIK). METHODS: A 36 …
Losartan inhibition of myofibroblast generation and late haze (scarring fibrosis) after PRK in rabbits
LP Sampaio, GSL Hilgert, TM Shiju… - Journal of Refractive …, 2022 - journals.healio.com
Purpose: To study the effect of topical losartan compared to vehicle on the generation of
myofibroblasts and development of late haze scarring fibrosis after photorefractive …
myofibroblasts and development of late haze scarring fibrosis after photorefractive …
A critical overview of the biological effects of mitomycin C application on the cornea following refractive surgery
E Arranz-Marquez, A Katsanos, VP Kozobolis… - Advances in …, 2019 - Springer
During the last 2 decades, modifying the shape of the cornea by means of laser
photoablation has emerged as a successful and popular treatment option for refractive …
photoablation has emerged as a successful and popular treatment option for refractive …
Epithelial basement membrane regeneration after PRK-induced epithelial-stromal injury in rabbits: fibrotic versus non-fibrotic corneal healing
RC de Oliveira, LP Sampaio, TM Shiju… - Journal of Refractive …, 2022 - journals.healio.com
PURPOSE: To study epithelial basement membrane (EBM) regeneration in non-fibrotic and
fibrotic corneas after photorefractive keratectomy (PRK). METHODS: Rabbits (120 total) had …
fibrotic corneas after photorefractive keratectomy (PRK). METHODS: Rabbits (120 total) had …
Biology of keratorefractive surgery-PRK, PTK, LASIK, SMILE, inlays and other refractive procedures
SE Wilson - Experimental eye research, 2020 - Elsevier
The outcomes of refractive surgical procedures to improve uncorrected vision in patients—
including photorefractive keratectomy (PRK), laser in-situ keratomileusis (LASIK), Small …
including photorefractive keratectomy (PRK), laser in-situ keratomileusis (LASIK), Small …
Early clinical outcomes and comparison between trans-PRK and PRK, regarding refractive outcome, wound healing, pain intensity and visual recovery time in a real …
HC Gaeckle - BMC ophthalmology, 2021 - Springer
Purpose To compare early clinical outcomes of single-step transepithelial photorefractive
keratectomy (tPRK) and photorefractive keratectomy (PRK) regarding refractive outcome …
keratectomy (tPRK) and photorefractive keratectomy (PRK) regarding refractive outcome …
Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK
RC de Oliveira, SE Wilson - Experimental eye research, 2020 - Elsevier
This review details the current understanding of the mechanism of action and corneal effects
of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive …
of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive …
Management of corneal haze after photorefractive keratectomy
M Moshirfar, Q Wang, J Theis, KC Porter… - Ophthalmology and …, 2023 - Springer
Photorefractive keratectomy (PRK) is a safe and popular corneal surgery performed
worldwide. Nevertheless, there is potential risk of corneal haze development after surgery …
worldwide. Nevertheless, there is potential risk of corneal haze development after surgery …