The role of medical image modalities and AI in the early detection, diagnosis and grading of retinal diseases: a survey

GA Saleh, NM Batouty, S Haggag, A Elnakib, F Khalifa… - Bioengineering, 2022 - mdpi.com
Traditional dilated ophthalmoscopy can reveal diseases, such as age-related macular
degeneration (AMD), diabetic retinopathy (DR), diabetic macular edema (DME), retinal tear …

Imaging retinal activity in the living eye

JJ Hunter, WH Merigan… - Annual review of vision …, 2019 - annualreviews.org
Retinal function has long been studied with psychophysical methods in humans, whereas
detailed functional studies of vision have been conducted mostly in animals owing to the …

High-speed adaptive optics line-scan OCT for cellular-resolution optoretinography

VP Pandiyan, X Jiang, A Maloney-Bertelli… - Biomedical optics …, 2020 - opg.optica.org
Optoretinography–the non-invasive, optical imaging of light-induced functional activity in the
retina–stands to provide a critical biomarker for testing the safety and efficacy of new …

Approach for a clinically useful comprehensive classification of vascular and neural aspects of diabetic retinal disease

MD Abramoff, PE Fort, IC Han… - … & visual science, 2018 - iovs.arvojournals.org
Abstract The Early Treatment Diabetic Retinopathy Study (ETDRS) and other standardized
classification schemes have laid a foundation for tremendous advances in the …

In vivo optoretinography of phototransduction activation and energy metabolism in retinal photoreceptors

G Ma, T Son, TH Kim, X Yao - Journal of biophotonics, 2021 - Wiley Online Library
The objective of this study is to verify the anatomic correlate of the second (2nd) outer retina
band in optical coherence tomography (OCT), and to demonstrate the potential of using …

Planar polarity in primate cone photoreceptors: a potential role in Stiles Crawford effect phototropism

A Verschueren, L Boucherit, U Ferrari… - Communications …, 2022 - nature.com
Human cone phototropism is a key mechanism underlying the Stiles-Crawford effect, a
psychophysiological phenomenon according to which photoreceptor outer/inner segments …

Advances in retinal imaging for diabetic retinopathy and diabetic macular edema

CSH Tan, MCY Chew, LWY Lim… - Indian journal of …, 2016 - journals.lww.com
Diabetic retinopathy and diabetic macular edema (DME) are leading causes of blindness
throughout the world, and cause significant visual morbidity. Ocular imaging has played a …

Measurement of diurnal variation in rod outer segment length in vivo in mice with the OCT optoretinogram

P Zhang, B Shibata, G Peinado… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: To investigate diurnal variation in the length of mouse rod outer segments in vivo.
Methods: The lengths of rod inner and outer segments (RIS, ROS) of dark-adapted albino …

Functional intrinsic optical signal imaging for objective optoretinography of human photoreceptors

T Son, TH Kim, G Ma, H Kim… - Experimental Biology and …, 2021 - journals.sagepub.com
Functional mapping of photoreceptor physiology is important for better disease diagnosis
and treatment assessment. Fast intrinsic optical signal (IOS), which arises before light …

Volumetric data analysis enabled spatially resolved optoretinogram to measure the functional signals in the living retina

L Zhang, R Dong, RJ Zawadzki… - Journal of …, 2022 - Wiley Online Library
Optoretinogram, a technique in which optical coherence tomography (OCT) is used to
measure retinal functions in response to a visible light stimulus, can be a potentially useful …