The ability to construct and maintain a structured multicellular bacterial community depends
critically on the production of extracellular matrix components (1, 2). While the biofilm matrix …

Pseudomonas aeruginosa is one of the main microbial species colonizing the lungs of cystic
fibrosis patients and is responsible for the decline in respiratory function. Despite the hostile …

Pseudomonas aeruginosa is a ubiquitous environmental bacterium which causes
opportunistic human infections. A large number of metabolic pathways and regulatory genes …

Bacterial programmed cell death and quorum sensing are direct examples of prokaryote
group behaviors, wherein cells coordinate their actions to function cooperatively like one …

The opportunistic pathogen Pseudomonas aeruginosa causes serious human infections, but
effective treatments and the mechanisms mediating pathogenesis remain elusive …

Determining bacterial gene expression during infection is fundamental to understand
pathogenesis. In this study, we used dual RNA-seq to simultaneously measure P …

Pseudomonas aeruginosa strain PA14 is an opportunistic human pathogen capable of
infecting a wide range of organisms including the nematode Caenorhabditis elegans. We …

Despite years of research and clinical advances, chronic pulmonary infections with mucoid
Pseudomonas aeruginosa remain the primary concern for cystic fibrosis patients. Much of …

A vast range of extracellular polysaccharides are produced by bacteria in order to adapt to
and thrive in diverse environmental niches. Many of these polymers have attracted great …

Pseudomonas aeruginosa is an opportunistic pathogen causing severe infections often
characterized by robust neutrophilic infiltration. Neutrophils provide the first line of defense …