Metabolic therapy of heart failure: Is there a future for B vitamins?
J Piquereau, SE Boitard, R Ventura-Clapier… - International Journal of …, 2021 - mdpi.com
Heart failure (HF) is a plague of the aging population in industrialized countries that
continues to cause many deaths despite intensive research into more effective treatments …
continues to cause many deaths despite intensive research into more effective treatments …
Impaired coenzyme A homeostasis in cardiac dysfunction and benefits of boosting coenzyme A production with vitamin B5 and its derivatives in the management of …
JJ Wedman, OCM Sibon… - Journal of Inherited …, 2024 - Wiley Online Library
Coenzyme A (CoA) is an essential cofactor required for over a hundred metabolic reactions
in the human body. This cofactor is synthesized de novo in our cells from vitamin B5, also …
in the human body. This cofactor is synthesized de novo in our cells from vitamin B5, also …
Dexpanthenol attenuates inflammatory damage and apoptosis in kidney and liver tissues of septic mice
X Zhao, S Zhang, H Shao - Bioengineered, 2022 - Taylor & Francis
Sepsis is capable of causing systemic infections resulting in multiple organ damage.
Dexpanthenol (DXP) has been reported to protect against kidney and liver injury. Therefore …
Dexpanthenol (DXP) has been reported to protect against kidney and liver injury. Therefore …
Protective effects of dexpanthenol in carbon tetrachloride-induced myocardial toxicity in rats
Exposure to various organic compounds including several environmental pollutants and
drugs can cause cellular damage through the generation of lipid peroxidation products …
drugs can cause cellular damage through the generation of lipid peroxidation products …
Neuroprotective effects of dexpanthenol on rabbit spinal cord ischemia/reperfusion injury model
A Gülmez, PK Bektaşoğlu, Ç Tönge, A Yaprak… - World Neurosurgery, 2022 - Elsevier
Objective Dexpanthenol (DXP) reportedly protects tissues against oxidative damage in
various inflammation models. This study aimed to evaluate its effects on oxidative stress …
various inflammation models. This study aimed to evaluate its effects on oxidative stress …
Dexpanthenol ameliorates doxorubicin-induced lung injury by regulating endoplasmic reticulum stress and apoptosis
Doxorubicin (DOX), which is used as a chemotherapeutic agent in the treatment of tumors,
has limited use due to its toxicity in various organs and tissues. One of the organs where …
has limited use due to its toxicity in various organs and tissues. One of the organs where …
Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin
Background Despite the available treatments, pulmonary arterial hypertension (PAH)
prognosis is poor. Objectives We aimed to investigate the effects of the alamandine (ALA) …
prognosis is poor. Objectives We aimed to investigate the effects of the alamandine (ALA) …
Fraxin in Combination with Dexamethasone Attenuates LPS‐Induced Liver and Heart Injury and Their Anticytokine Activity in Mice
Background. Cytokine storm syndrome (CSS) is a major cause of morbidity and mortality in
people suffering from hyperinflammatory status, which diverse etiological factors, including …
people suffering from hyperinflammatory status, which diverse etiological factors, including …
Circular RNA protein tyrosine kinase 2 aggravates pyroptosis and inflammation in septic lung tissue by promoting microRNA-766/eukaryotic initiation factor 5A axis …
FY Ding, JL Zhu, YL Hu - Acta Cirúrgica Brasileira, 2023 - SciELO Brasil
Purpose: Sepsis is characterized by an acute inflammatory response to infection, often with
multiple organ failures, especially severe lung injury. This study was implemented to probe …
multiple organ failures, especially severe lung injury. This study was implemented to probe …
The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis
Aim Early and prompt treatment of sepsis by effective antibiotics against susceptible
organisms may be lifesaving. However, increased antibiotic resistance and side effects of …
organisms may be lifesaving. However, increased antibiotic resistance and side effects of …