The neurology of mTOR

JO Lipton, M Sahin - Neuron, 2014 - cell.com
The mechanistic target of rapamycin (mTOR) signaling pathway is a crucial cellular
signaling hub that, like the nervous system itself, integrates internal and external cues to …

Sleep, clocks, and synaptic plasticity

MG Frank, R Cantera - Trends in neurosciences, 2014 - cell.com
Sleep is widely believed to play an essential role in synaptic plasticity. However, the precise
mechanisms governing this presumptive function are largely unknown. There is also …

System consolidation during sleep–a common principle underlying psychological and immunological memory formation

J Westermann, T Lange, J Textor, J Born - Trends in neurosciences, 2015 - cell.com
Sleep benefits the consolidation of psychological memory, and there are hints that sleep
likewise supports immunological memory formation. Comparing psychological and …

Sleep and synaptic plasticity in the developing and adult brain

MG Frank - Sleep, neuronal plasticity and brain function, 2015 - Springer
Sleep is hypothesized to play an integral role in brain plasticity. This has traditionally been
investigated using behavioral assays. In the last 10–15 years, studies combining sleep …

Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress

J Grønli, J Soulé, CR Bramham - Frontiers in behavioral neuroscience, 2014 - frontiersin.org
Sleep has been ascribed a critical role in cognitive functioning. Several lines of evidence
implicate sleep in the consolidation of synaptic plasticity and long-term memory. Stress …

The ontogenesis of mammalian sleep: form and function

MG Frank - Current sleep medicine reports, 2020 - Springer
Abstract Purpose of Review To present an up-to-date review and synthesis of findings about
perinatal sleep development and function. I discuss landmark events in sleep ontogenesis …

Experience and sleep-dependent synaptic plasticity: from structure to activity

L Sun, H Zhou, J Cichon… - … Transactions of the …, 2020 - royalsocietypublishing.org
Synaptic plasticity is important for learning and memory. With increasing evidence linking
sleep states to changes in synaptic strength, an emerging view is that sleep promotes …

[HTML][HTML] Dietary polyphenols promote resilience against sleep deprivation–induced cognitive impairment by activating protein translation

T Frolinger, C Smith, CF Cobo, S Sims… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Previous evidence has suggested that dietary supplementation with a bioactive dietary
polyphenol preparation (BDPP) rescues impairment of hippocampus-dependent memory in …

Molecular mechanisms of memory consolidation that operate during sleep

I Reyes-Resina, S Samer, MR Kreutz… - Frontiers in Molecular …, 2021 - frontiersin.org
The role of sleep for brain function has been in the focus of interest for many years. It is now
firmly established that sleep and the corresponding brain activity is of central importance for …

Wakefulness/sleep architecture and electroencephalographic activity in mice lacking the translational repressor 4E-BP1 or 4E-BP2

CC Areal, R Cao, N Sonenberg, V Mongrain - Sleep, 2020 - academic.oup.com
Sleep and sleep loss are affecting protein synthesis in the brain, but the contribution of
translational control to wakefulness and sleep regulation remains poorly understood. Here …