Analyzing high-dimensional cytometry data using FlowSOM

K Quintelier, A Couckuyt, A Emmaneel, J Aerts… - Nature protocols, 2021 - nature.com
The dimensionality of cytometry data has strongly increased in the last decade, and in many
situations the traditional manual downstream analysis becomes insufficient. The field is …

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19

M Lourda, M Dzidic, L Hertwig… - Proceedings of the …, 2021 - National Acad Sciences
Since the outset of the COVID-19 pandemic, increasing evidence suggests that the innate
immune responses play an important role in the disease development. A dysregulated …

Increased IL‐10‐producing regulatory T cells are characteristic of severe cases of COVID‐19

J Neumann, T Prezzemolo… - Clinical & …, 2020 - Wiley Online Library
Objectives The pandemic spread of the coronavirus SARS‐CoV‐2 is due, in part, to the
immunological properties of the host–virus interaction. The clinical presentation varies from …

Natural killer cell activation related to clinical outcome of COVID-19

C Maucourant, I Filipovic, A Ponzetta, S Aleman… - medRxiv, 2020 - medrxiv.org
Understanding innate immune responses in COVID-19 is important for deciphering
mechanisms of host responses and interpreting disease pathogenesis. Natural killer (NK) …

A Little Complement Goes a Long Way: Neisseria gonorrhoeae and Membrane-Bound Complement Inhibitors

PM Zdinak - 2020 - rave.ohiolink.edu
Neisseria gonorrhoeae is the causative agent of gonorrhea infection. The Center for
Disease Control estimates that over 800,000 gonorrhea infections occur in the United States …