Formulation stabilization and disaggregation of bevacizumab, ranibizumab and aflibercept in dilute solutions

SA Giannos, ER Kraft, ZY Zhao, KH Merkley… - Pharmaceutical …, 2018 - Springer
Purpose Studies were conducted to investigate dilute solutions of the monoclonal antibody
(mAb) bevacizumab, mAb fragment ranibizumab and fusion protein aflibercept, develop …

Optimization and characterization of spray-dried IgG formulations: a design of experiment approach

H Faghihi, AR Najafabadi, A Vatanara - DARU Journal of Pharmaceutical …, 2017 - Springer
Background The purpose of the present study is to optimize a spray-dried formulation as a
model antibody regarding stability and aerodynamic property for further aerosol therapy of …

IMGT/mAb-KG: the knowledge graph for therapeutic monoclonal antibodies

G Sanou, T Manso, K Todorov, V Giudicelli… - Frontiers in …, 2024 - frontiersin.org
Introduction Therapeutic monoclonal antibodies (mAbs) have demonstrated promising
outcomes in diverse clinical indications, including but not limited to graft rejection, cancer …

Clinical applications of protein-based therapeutics

MK Yadav, A Sahu, Anu, N Kasturria… - Protein-Based …, 2023 - Springer
Regarded as highly successful in their clinical applications, therapeutic proteins are now
widely applied for the precise treatment of several diseases. Common forms of therapeutic …

[图书][B] Bionanotechnology: Principles and Applications

AK Anal - 2018 - taylorfrancis.com
This book deals with a subject of high interest and importance in all sectors, including
biomedical, food, agriculture, energy, and environment. Biological systems are essential in …

PTGFRN as a Target for Antibody-Drug Conjugate (ADC) Development in Mesothelioma and Medulloblastoma

J Marquez - 2023 - archive.hshsl.umaryland.edu
Cancer is a disease that afflicts millions of people each year. While there are many drugs
available to treat certain subsets of cancer, there still remain many types of cancer that do …

[PDF][PDF] Λειτουργική μελέτη των κλωνοτυπικών ανοσοσφαιρινών σε ασθενείς με Β λεμφώματα

ΕΠ Κοτρώνη - 2023 - ir.lib.uth.gr
Περίληψη Η λειτουργική μελέτη των ανοσοσφαιρινών αποτελεί ένα από τα σημαντικότερα
ερευνητικά βήματα για τη βαθύτερη κατανόηση της οντογένεσης των Β λεμφωμάτων. Με …

Single-Column Chromatography with Recycle Lag Analog to Simulated Moving Bed Processes

AS Chibério - 2019 - search.proquest.com
The chromatography steps dominate the Downstream Processing (DSP) costs of a new
biopharmaceutical, which has propelled the biopharmaceutical industry to invest a lot of …