YAP and TAZ are intracellular messengers communicating multiple interacting extracellular
biophysical and biochemical cues to the transcription apparatus in the nucleus and back to …

Yes-associated protein, a core regulator of the Hippo-YAP signaling pathway, plays a vital
role in inhibiting apoptosis. Thus, several studies and reviews suggest that yes-associated …

Recent evidence has indicated that overexpression of the epigenetic reader bromodomain‐
containing protein 4 (BRD4) contributes to a poor prognosis of lung cancers, and the …

Anaplastic large cell lymphomas (ALCLs) represent a relatively common group of T-cell non-
Hodgkin lymphomas (T-NHLs) that are unified by similar pathologic features but …

This review provides an overview of histopathology, clinical presentation, molecular
pathways, and potential new systemic treatments of high-grade chondrosarcomas (CS) …

Abstract Background Thymic epithelial tumors (TETs) are rare neoplasms, originating from
epithelial thymic cells. The oncogenic potential of these rare neoplasms is still largely …

Proteolysis-targeting chimeras (PROTACs) have recently been of great interest in cancer
therapy. However, the bioavailability of PROTACs is considerably restricted due to their high …

Long non-coding RNAs (lncRNAs) have extremely complex roles in the progression of
intrahepatic cholangiocarcinoma (ICC) and remain to be elucidated. By cytological and …

Hippo/YAP1 signaling is a major regulator of organ size, cancer stemness, and aggressive
phenotype. Thus, targeting YAP1 may provide a novel therapeutic strategy for tumors with …

Kurarinone (KR), a naturally occurring flavonoid in Sophora flavescens Aiton and a
traditional herbal medicine, reportedly has anti-cancer activity against various cancer types …