Early life microbial exposures and allergy risks: opportunities for prevention

H Renz, C Skevaki - Nature Reviews Immunology, 2021 - nature.com
Allergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence,
particularly in westernized countries. Although a detailed mechanistic explanation for this …

The microbiome in early life: implications for health outcomes

S Tamburini, N Shen, HC Wu, JC Clemente - Nature medicine, 2016 - nature.com
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …

Association of infant antibiotic exposure with childhood health outcomes

Z Aversa, EJ Atkinson, MJ Schafer, RN Theiler… - Mayo Clinic …, 2021 - Elsevier
Objective To investigate the extent to which antibiotic exposure in the first 2 years of life is
associated with the risk of immunological, metabolic, and neurobehavioral health conditions …

[HTML][HTML] Antibiotics and the human gut microbiome: dysbioses and accumulation of resistances

MP Francino - Frontiers in microbiology, 2016 - frontiersin.org
The human microbiome is overly exposed to antibiotics, due, not only to their medical use,
but also to their utilization in farm animals and crops. Microbiome composition can be rapidly …

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

K Korpela, A Salonen, LJ Virta, RA Kekkonen… - Nature …, 2016 - nature.com
Early-life antibiotic use is associated with increased risk for metabolic and immunological
diseases, and mouse studies indicate a causal role of the disrupted microbiome. However …

Impact of antibiotics on the human microbiome and consequences for host health

DV Patangia, C Anthony Ryan, E Dempsey… - …, 2022 - Wiley Online Library
It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

[HTML][HTML] Factors influencing the gut microbiota, inflammation, and type 2 diabetes

L Wen, A Duffy - The Journal of nutrition, 2017 - Elsevier
The gut microbiota is a complex community of bacteria residing in the intestine. Animal
models have demonstrated that several factors contribute to and can significantly alter the …

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

S Leclercq, FM Mian, AM Stanisz, LB Bindels… - Nature …, 2017 - nature.com
There is increasing concern about potential long-term effects of antibiotics on children's
health. Epidemiological studies have revealed that early-life antibiotic exposure can …

Antibiotic-induced changes in the intestinal microbiota and disease

S Becattini, Y Taur, EG Pamer - Trends in molecular medicine, 2016 - cell.com
The gut microbiota is a key player in many physiological and pathological processes
occurring in humans. Recent investigations suggest that the efficacy of some clinical …

[HTML][HTML] Antibiotic exposure and adverse long-term health outcomes in children: a systematic review and meta-analysis

QA Duong, LF Pittet, N Curtis, P Zimmermann - Journal of Infection, 2022 - Elsevier
Background Antibiotics are amongst the most commonly used drugs in children. In addition
to inducing antibiotic resistance, antibiotic exposure has been associated with adverse long …