Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
FF Gonzalez-Galarza, A McCabe… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Allele Frequency Net Database (AFND, www. allelefrequencies. net) provides
the scientific community with a freely available repository for the storage of frequency data …
the scientific community with a freely available repository for the storage of frequency data …
Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles
J Robinson, LA Guethlein, N Cereb, SY Yang… - PLoS …, 2017 - journals.plos.org
HLA class I glycoproteins contain the functional sites that bind peptide antigens and engage
lymphocyte receptors. Recently, clinical application of sequence-based HLA typing has …
lymphocyte receptors. Recently, clinical application of sequence-based HLA typing has …
A snapshot of human leukocyte antigen (HLA) diversity using data from the Allele Frequency Net Database
FF Gonzalez-Galarza, A McCabe, EJM Dos Santos… - Human Immunology, 2021 - Elsevier
The extensive allelic variability observed in several genes related to the immune response
and its significance in different areas including transplantation, disease association studies …
and its significance in different areas including transplantation, disease association studies …
Relevance of polymorphic KIR and HLA class I genes in NK-cell-based immunotherapies for adult leukemic patients
L Dubreuil, P Chevallier, C Retière, K Gagne - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapies are promising approaches to curing different acute
leukemias. Natural killer (NK) cells are lymphocytes that are efficient in the elimination of …
leukemias. Natural killer (NK) cells are lymphocytes that are efficient in the elimination of …
Common and well‐documented HLA alleles over all of Europe and within European sub‐regions: a catalogue from the European Federation for Immunogenetics
Background A catalogue of common and well‐documented (CWD) human leukocyte antigen
(HLA), previously established by the American Society for Histocompatibility and …
(HLA), previously established by the American Society for Histocompatibility and …
[HTML][HTML] The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure
R Barquera, DI Hernández-Zaragoza… - Human Immunology, 2020 - Elsevier
We studied HLA class I (HLA-A,-B) and class II (HLA-DRB1,-DQB1) allele groups and alleles
by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all the states of …
by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all the states of …
[PDF][PDF] Precision neoantigen discovery using large-scale immunopeptidomes and composite modeling of MHC peptide presentation
Precision Neoantigen Discovery Using Large-scale Immunopeptidomes and Composite
Modeling of MHC Peptide Presentation Page 1 Precision Neoantigen Discovery Using …
Modeling of MHC Peptide Presentation Page 1 Precision Neoantigen Discovery Using …
Predictive immunogenetic markers in COVID-19
M de Meira Leite, FF Gonzalez-Galarza… - Human Immunology, 2021 - Elsevier
Immunorelevant genes are among the most probable modulators of coronavirus disease
2019 (COVID-19) progression and prognosis. However, in the few months of the pandemic …
2019 (COVID-19) progression and prognosis. However, in the few months of the pandemic …
Allele frequency net database
FF Gonzalez-Galarza, A McCabe… - HLA typing: methods …, 2018 - Springer
The allele frequency net database (AFND, http://www. allelefrequencies. net) is an online
web-based repository that contains information on the frequencies of immune-related genes …
web-based repository that contains information on the frequencies of immune-related genes …
Improved HLA typing of Class I and Class II alleles from next‐generation sequencing data
Precise HLA genotyping is of great clinical importance, albeit a challenging bioinformatics
endeavor because of the hyper polymorphism of the HLA region. The ever‐increasing …
endeavor because of the hyper polymorphism of the HLA region. The ever‐increasing …