Ovarian carcinomas comprise a heterogeneous group of neoplasms, the four most common
subtypes being serous, endometrioid, clear cell and mucinous. In recent years, our …

Ovarian cancer is a deadly disease for which there is no effective means of early detection.
Ovarian carcinomas comprise a diverse group of neoplasms, exhibiting a wide range of …

Activating mutations in KRAS and in one of its downstream mediators, BRAF, have been
identified in a variety of human cancers. To determine the role of mutations in BRAF and …

Endometriosis is an estrogen-dependent disorder where endometrial tissue forms lesions
outside the uterus. Endometriosis affects an estimated 10% of women in the reproductive …

OBJECTIVE: This article represents a review of histologic and genetic findings in
endometriosis and describes the mechanisms whereby genetic and non-genetic factors …

Although the histologic diagnosis of endometriosis is usually straightforward, many
diagnostic problems can arise as a result of alterations or absence of its glandular or stromal …

Epithelial ovarian cancer comprises the majority of malignant ovarian tumors in adult
women. These neoplasms are classified into distinct morphologic categories based on the …

For several decades, endometriosis has been suspected of playing a role in the aetiology of
ovarian cancer. The literature concerning a possible histogenesis of ovarian cancer from …

BACKGROUND: Several observations of the coexistence of endometriosis and cancer have
been published. One study concerning endometriosis patients from 1969 to 1986 showed …

Purpose: Endometriotic cysts are known to transform into ovarian cancers, such as clear cell
and endometrioid carcinomas. We hypothesized that an iron-rich environment produced by …