SARS-CoV-2 variants, vaccines, and host immunity

P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …

A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2022 - frontiersin.org
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

B Yan, T Freiwald, D Chauss, L Wang, E West… - Science …, 2021 - science.org
Patients with coronavirus disease 2019 (COVID-19) present a wide range of acute clinical
manifestations affecting the lungs, liver, kidneys, and gut. Angiotensin-converting enzyme 2 …

Pathogenesis of respiratory viral and fungal coinfections

F Salazar, E Bignell, GD Brown, PC Cook… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

M Stravalaci, I Pagani, EM Paraboschi, M Pedotti… - Nature …, 2022 - nature.com
The humoral arm of innate immunity includes diverse molecules with antibody-like functions,
some of which serve as disease severity biomarkers in coronavirus disease 2019 (COVID …

COVID-19 vaccine side effects: The positives about feeling bad

J Sprent, C King - Science immunology, 2021 - science.org
COVID-19 vaccine side effects: The positives about feeling bad | Science Immunology news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …

Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein

M Yalcinkaya, W Liu, MN Islam, AG Kotini… - Scientific reports, 2021 - nature.com
Despite the initial success of some drugs and vaccines targeting COVID-19, understanding
the mechanism underlying SARS-CoV-2 disease pathogenesis remains crucial for the …

[HTML][HTML] Parsing the role of NSP1 in SARS-CoV-2 infection

T Fisher, A Gluck, K Narayanan, M Kuroda… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to shutoff of protein
synthesis, and nsp1, a central shutoff factor in coronaviruses, inhibits cellular mRNA …

Upregulated type I interferon responses in asymptomatic COVID-19 infection are associated with improved clinical outcome

KI Masood, M Yameen, J Ashraf, S Shahid… - Scientific reports, 2021 - nature.com
Understanding key host protective mechanisms against SARS-CoV-2 infection can help
improve treatment modalities for COVID-19. We used a blood transcriptome approach to …