Adrenoleukodystrophy (ALD) is a rare X-linked disorder of peroxisomal oxidation due to
mutations in ABCD1. It is a progressive condition with a variable clinical spectrum that …

Background Over 80% of women with X-linked adrenoleukodystrophy (ALD) develop spinal
cord disease in adulthood for which treatment is supportive only. For future clinical trials …

Males with adrenoleukodystrophy develop progressive myelopathy causing severe disability
later in life. No treatment is currently available, but new disease-modifying therapies are …

Background Up to 80% of women with X‐linked adrenoleukodystrophy (X‐ALD) develop
symptoms of myelopathy and peripheral neuropathy during their lifetime. The study's …

Objective/background X-linked adrenoleukodystrophy (ALD) is a neurodegenerative
disease that causes progressive gait and balance problems. Leg discomfort, sleep …

Abstract X‐linked adrenoleukodystrophy (X‐ALD) is an inherited disease characterized by
progressive inflammatory demyelization in the brain, adrenal insufficiency, and an abnormal …

X-linked adrenoleukodystrophy is a common X-linked recessive peroxisomal disorder
caused by the mutations in the ABCD1 gene. In this study, we analyzed 19 male patients …

X-linked adrenoleukodystrophy (X-ALD, OMIM# 300100) is the most common peroxisomal
disorder clinically characterized by two main phenotypes: adrenomyeloneuropathy (AMN) …

X-linked adrenoleukodystrophy (X-ALD, OMIM# 300100) is the most common peroxisomal
disorder clinically characterized by two main phenotypes: adrenomyeloneuropathy (AMN) …

Adrenoleukodystrophy (X-ALD) is a rare X-linked peroxisomal disease, which usually
presents in affected males with one of three phenotypes: adult-onset …