Dopamine beta‐hydroxylase and its genetic variants in human health and disease

E Gonzalez‐Lopez, KE Vrana - Journal of neurochemistry, 2020 - Wiley Online Library
Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme
that catalyzes the formation of norepinephrine (NE) from dopamine and has been …

Family and psychosocial functioning in bipolar disorder: the mediating effects of social support, resilience and suicidal ideation

W Dou, X Yu, H Fang, D Lu, L Cai, C Zhu… - Frontiers in …, 2022 - frontiersin.org
Patients with bipolar disorder (BD) may experience family dysfunction, which might result in
worse psychosocial functioning through environmental and psychological factors. Research …

Traumatic experiences, family functioning, and mood disorder development in bipolar offspring

MA Koenders, E Mesman, EJ Giltay… - British journal of …, 2020 - Wiley Online Library
Objectives Studies in children of patients affected with bipolar disorder (BD; bipolar
offspring) are at high risk to develop mood disorders. Our aim is to investigate how …

Intrinsic connectivity and family dynamics: Striatolimbic markers of risk and resilience in youth at familial risk for mood disorders

AS Fischer, B Holt-Gosselin, KE Hagan… - Biological Psychiatry …, 2022 - Elsevier
Background Few studies to date have characterized functional connectivity (FC) within
emotion and reward networks in relation to family dynamics in youth at high familial risk for …

Machine learning-based discrimination of unipolar depression and bipolar disorder with streamlined shortlist in adolescents of different ages

Y Wang, C Huang, P Li, B Niu, T Fan, H Wang… - Computers in Biology …, 2024 - Elsevier
Background Variations in symptoms and indistinguishable depression episodes of unipolar
depression (UD) and bipolar disorder (BD) make the discrimination difficult and time …

Changes in intrinsic brain connectivity in family-focused therapy versus standard psychoeducation among youths at high risk for bipolar disorder

MK Singh, AF Nimarko, AS Garrett, AJ Gorelik… - Journal of the American …, 2021 - Elsevier
Objective We compared intrinsic network connectivity in symptomatic youths at high risk
(HR) for bipolar disorder (BD) and healthy comparison (HC) youths. In HR youths, we also …

The mediating role of family functioning between childhood trauma and depression severity in major depressive disorder and bipolar disorder

Y Du, J Liu, R Lin, MR Chattun, W Gong, L Hua… - Journal of Affective …, 2024 - Elsevier
Background Childhood trauma (CT) and family functioning exert significant influences on the
course and long-term outcome of major depressive disorder (MDD) and bipolar disorder …

Examining the association of familial and social stress, trauma, and support on mood, anxiety, and behavioral symptoms and diagnoses in youth at risk for bipolar …

M Kamali, EK Stapp, JM Fullerton, N Ghaziuddin… - Journal of affective …, 2024 - Elsevier
Introduction Youth with a family history of bipolar disorder (At-Risk) have a higher risk of
developing psychiatric disorders and experiencing environmental stressors than youth …

Cortical mediation of relationships between dopamine receptor D2 and cognition is absent in youth at risk of bipolar disorder

BJ Overs, RK Lenroot, G Roberts, MJ Green… - Psychiatry Research …, 2021 - Elsevier
Bipolar disorder is associated with cognitive deficits and cortical changes for which the
developmental dynamics are not well understood. The dopamine D2 receptor (DRD2) gene …

The COMT rs4680 polymorphism, family functioning and preschoolers' attentional control indexed by intraindividual reaction time variability

Y Zhang, X Yang, Z Wang - Developmental Psychobiology, 2021 - Wiley Online Library
Trial‐to‐trial intraindividual reaction time variability (IIRTV) serves as an index of attentional
control and related endogenous brain function. What determinants contribute to …