Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as" resting versus activated" and" M1 versus M2." …

Microglia are resident immune cells in the central nervous system (CNS) that are capable of
carrying out prominent and various functions during development and adulthood under both …

Microglia were first recognized as a distinct cell population in the CNS one century ago. For
a long time, they were primarily considered to be phagocytes responsible for removing …

Activation of microglia is a prominent pathological feature in tauopathies, including
Alzheimer's disease. How microglia activation contributes to tau toxicity remains largely …

Based on discoveries enabled by new technologies and analysis using novel computational
tools, neuroscience can be re-conceived in terms of information exchange in dense …

Microglia, the brain's immune sentinels, have garnered much attention in recent years.
Researchers have begun to identify the manifold roles that these cells play in the central …

The retina is a complex tissue with multiple cell layers that are highly ordered. Its
sophisticated structure makes it especially sensitive to external or internal perturbations that …

Microglia and central nervous system (CNS)-associated macrophages (CAMs), such as
perivascular and meningeal macrophages, are implicated in virtually all diseases of the …

Microglia are important immune cells in the central nervous system (CNS) that undergo
turnover throughout the lifespan. If microglial debris is not removed in a timely manner …

Microglia are emerging as key drivers of neurological diseases. However, we lack a
systematic understanding of the underlying mechanisms. Here, we present a screening …