Glutathione (GSH) is the most abundant non-protein thiol present at millimolar
concentrations in mammalian tissues. As an important intracellular antioxidant, it acts as a …

The development of new accelerators has given a new impetus to the development of new
drugs and treatment technologies using boron neutron capture therapy (BNCT). We …

Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

Many cancers have long been thought to primarily metabolize glucose for energy production—
a phenomenon known as the Warburg Effect, after the classic studies of Otto Warburg in the …

Cancer is a devastating disease that alters the metabolism of a cell and the surrounding
milieu. Metabolomics is a growing and powerful technology capable of detecting hundreds …

Machine learning uses experimental data to optimize clustering or classification of samples
or features, or to develop, augment or verify models that can be used to predict behavior or …

Extracellular vesicles (EVs) are highly diverse nanoscale membrane-bound structures
released from different cell types into the extracellular environment. They play essential …

The most common malignant brain tumors are those of astrocytic origin, gliomas, with the
most aggressive glioblastoma (WHO grade IV) among them. Despite efforts, medicine has …

Metabolomics combined with machine learning methods (MLMs), is a powerful tool for
searching novel diagnostic panels. This study was intended to use targeted plasma …

Gliomas are highly lethal tumours characterised by heterogeneous molecular features,
producing various metabolic phenotypes leading to therapeutic resistance. Lipid metabolism …