Organic electrochemical transistors in bioelectronic circuits
The organic electrochemical transistor (OECT) represents a versatile and impactful
electronic building block in the areas of printed electronics, bioelectronics, and …
electronic building block in the areas of printed electronics, bioelectronics, and …
Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry
BW Pogue, MS Patterson - Journal of biomedical optics, 2006 - spiedigitallibrary.org
Optical spectroscopy, imaging, and therapy tissue phantoms must have the scattering and
absorption properties that are characteristic of human tissues, and over the past few …
absorption properties that are characteristic of human tissues, and over the past few …
[HTML][HTML] LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells
A Brand, K Singer, GE Koehl, M Kolitzus… - Cell metabolism, 2016 - cell.com
Elevated lactate dehydrogenase A (LDHA) expression is associated with poor outcome in
tumor patients. Here we show that LDHA-associated lactic acid accumulation in melanomas …
tumor patients. Here we show that LDHA-associated lactic acid accumulation in melanomas …
Role of monocarboxylate transporters in human cancers: state of the art
C Pinheiro, A Longatto-Filho, J Azevedo-Silva… - Journal of bioenergetics …, 2012 - Springer
Monocarboxylate transporters (MCTs) belong to the SLC16 gene family, presently
composed by 14 members. MCT1-MCT4 are proton symporters, which mediate the …
composed by 14 members. MCT1-MCT4 are proton symporters, which mediate the …
Lactate: mirror and motor of tumor malignancy
S Walenta, WF Mueller-Klieser - Seminars in radiation oncology, 2004 - Elsevier
A number of studies have shown that malignant transformation is associated with an
increase in glycolytic flux and in anaerobic and aerobic cellular lactate excretion. Using …
increase in glycolytic flux and in anaerobic and aerobic cellular lactate excretion. Using …
Molecular imaging of hypoxia
Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy
GD Maurer, DP Brucker, O Bähr, PN Harter… - BMC cancer, 2011 - Springer
Background Even in the presence of oxygen, malignant cells often highly depend on
glycolysis for energy generation, a phenomenon known as the Warburg effect. One strategy …
glycolysis for energy generation, a phenomenon known as the Warburg effect. One strategy …
Chemical mapping of tumor progression by FT-IR imaging: towards molecular histopathology
C Petibois, G Déléris - TRENDS in Biotechnology, 2006 - cell.com
Fourier-transform infrared (FT-IR) spectro-imaging enables global analysis of samples, with
resolution close to the cellular level. Recent studies have shown that FT-IR imaging enables …
resolution close to the cellular level. Recent studies have shown that FT-IR imaging enables …
[PDF][PDF] Lactate detection in tumor cell cultures using organic transistor circuits
However, some key issues still impede their practical implementation in a clinical setting.
These issues include signal drift due to environmental changes (eg, electrolyte evaporation …
These issues include signal drift due to environmental changes (eg, electrolyte evaporation …
Multizone paper platform for 3D cell cultures
In vitro 3D culture is an important model for tissues in vivo. Cells in different locations of 3D
tissues are physiologically different, because they are exposed to different concentrations of …
tissues are physiologically different, because they are exposed to different concentrations of …