Revisiting the dose constraints for head and neck OARs in the current era of IMRT

NP Brodin, WA Tomé - Oral oncology, 2018 - Elsevier
Head and neck cancer poses a particular challenge in radiation therapy, whilst being an
effective treatment modality it requires very high doses of radiation to provide effective …

Normal tissue complication probability (NTCP) models for modern radiation therapy

G Palma, S Monti, M Conson, R Pacelli, L Cella - Seminars in oncology, 2019 - Elsevier
Mathematical models of normal tissue complication probability (NTCP) able to robustly
predict radiation-induced morbidities (RIM) play an essential role in the identification of a …

Systematic review of normal tissue complication models relevant to standard fractionation radiation therapy of the head and neck region published after the QUANTEC …

NP Brodin, R Kabarriti, MK Garg, C Guha… - International Journal of …, 2018 - Elsevier
There has recently been an increasing interest in model-based evaluation and comparison
of different treatment options in radiation oncology studies. This is partly driven by the …

Radiation-induced hypothyroidism after IMRT for nasopharyngeal carcinoma: Clinical and dosimetric predictors in a prospective cohort study

R Zhai, F Kong, C Du, C Hu, H Ying - Oral Oncology, 2017 - Elsevier
Objectives To investigate the rate and risk factors for developing hypothyroidism (HT) in
nasopharyngeal carcinoma (NPC) patients treated with intensity-modulated radiotherapy …

[HTML][HTML] Breast cancer, breast cancer-directed radiation therapy and risk of hypothyroidism: A systematic review and meta-analysis

E Solmunde, AM Falstie-Jensen, EL Lorenzen… - The Breast, 2023 - Elsevier
Objective Breast cancer and breast cancer-directed radiation therapy (RT) may increase the
risk of late effects, such as hypothyroidism. We conducted a systematic review and meta …

Generalizability assessment of head and neck cancer NTCP models based on the TRIPOD criteria

M Sharabiani, E Clementel, N Andratschke… - Radiotherapy and …, 2020 - Elsevier
This review aimed to provide an overview of the level of maturity of normal tissue
complication probability (NTCP) models for head and neck cancer (HNC) patients. A …

[HTML][HTML] Radiation therapy across pediatric Hodgkin lymphoma research group protocols: a report from the Staging, Evaluation, and Response Criteria Harmonization …

MD Hall, SA Terezakis, JT Lucas… - International Journal of …, 2022 - Elsevier
Radiotherapy (RT) technology and utilization has considerably evolved over the last 50
years in the management of pediatric Hodgkin lymphoma (HL). In response to significant …

Predictive performance of different NTCP techniques for radiation-induced esophagitis in NSCLC patients receiving proton radiotherapy

M Chen, Z Wang, S Jiang, J Sun, L Wang, N Sahoo… - Scientific reports, 2022 - nature.com
This study aimed to compare the predictive performance of different modeling methods in
developing normal tissue complication probability (NTCP) models for predicting radiation …

Dosimetric predictors of hypothyroidism after radical intensity-modulated radiation therapy for non-metastatic nasopharyngeal carcinoma

V Lee, SY Chan, CW Choi, D Kwong, KO Lam… - Clinical Oncology, 2016 - Elsevier
Aims To investigate dosimetric predictors of hypothyroidism after radical intensity-modulated
radiation therapy (IMRT) for non-metastatic nasopharyngeal carcinoma (NPC). Materials …

Dose-surface analysis for prediction of severe acute radio-induced skin toxicity in breast cancer patients

F Pastore, M Conson, V D'Avino, G Palma… - Acta …, 2016 - Taylor & Francis
Background: Severe acute radiation-induced skin toxicity (RIST) after breast irradiation is a
side effect impacting the quality of life in breast cancer (BC) patients. The aim of the present …